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Syringocystadenoma papilliferum is a rare non-malignant adnexal neoplasm that develops from apocrine or eccrine sweat glands and can be identified histologically by cystic, papillary, and ductal invaginations into the dermis lined by double-layered outer cuboidal and luminal high columnar epithelium and connected to the epidermis.
Hidrocystoma (also known as cystadenoma, [1] a Moll's gland cyst, [1] and a sudoriferous cyst [1]) is an adenoma of the sweat glands. [2]: 787 Hidrocystomas are cysts of sweat ducts, usually on the eyelids. [3]: 664 They are not tumours (a similar-sounding lesion called hidroadenoma is a benign tumour).
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Apocrine (/ ˈ æ p ə k r ɪ n /) [1] is a term used to classify the mode of secretion of exocrine glands. In apocrine secretion, secretory cells accumulate material at their apical ends, often forming blebs or "snouts", and this material then buds off from the cells, forming extracellular vesicles .
Acrospiromas are a broad class of benign cutaneous adnexal tumors. [1] Cutaneous adnexal tumors are a group of skin tumors consisting of tissues that have differentiated (i.e. matured from stem cells) towards one or more of the four primary adnexal structures found in normal skin: hair follicles, sebaceous sweat glands, apocrine sweat glands, and eccrine sweat glands. [2]
A papillary hidradenoma, also termed hidradenoma papilliferum or mammary-like gland adenoma of the vulva, [1] is a rare, but nonetheless most common benign tumor that occurs in and between anal and genital regions (i.e. anogenital area) of females. [2]
Hidradenoma refers to a benign adnexal tumor of the apical sweat gland. [1] [2] These are 1–3 cm translucent blue cystic nodules.It usually presents as a single, small skin-colored lesion, and may be considered closely related to or a variant of poromas. [3]
[1]: 663 They are skin-colored or yellowish firm, rounded bumps, 1–3 mm in diameter, and may be confused with xanthoma, milia, hidrocystoma, trichoepithelioma, and xanthelasma. [2] They are more common in women [ 3 ] and are most commonly found in middle-aged Asian women.