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Four motor symptoms are considered cardinal signs in PD: slowness of movement (bradykinesia), tremor, rigidity, and postural instability. [1] Typical for PD is an initial asymmetric distribution of these symptoms, where in the course of the disease, a gradual progression to bilateral symptoms develops, although some asymmetry usually persists.
Parkinsonism is a clinical syndrome characterized by tremor, bradykinesia (slowed movements), rigidity, and postural instability. [1] [2] Both hypokinetic (bradykinesia and akinesia) as well as hyperkinetic (cogwheel rigidity and tremors at rest) features are displayed by Parkinsonism. [3]
Bradykinesia has been shown to precede impairment of executive functions, working memory, and attention. [ 11 ] [ 31 ] These cognitive deficiencies can be tied to nonfunction of the basal ganglia and prefrontal cortex , which is also linked to the motor-dysfunction of hypokinesia. [ 11 ]
No cure for Parkinson's is known, and treatment focuses on alleviating symptoms. Initial treatment typically includes L-DOPA, MAO-B inhibitors, or dopamine agonists. As the disease progresses, these medications become less effective and may cause involuntary muscle movements. Diet and rehabilitation therapies can help improve symptoms.
A feeling of pressure and squeezing in the chest is a serious indication that medical care is essential because chest pain and discomfort is one of the most common symptoms of heart attack in men.
Medications are used to reverse the symptoms of extrapyramidal side effects caused by antipsychotics or other drugs, by either directly or indirectly increasing dopaminergic neurotransmission. The treatment varies by the type of the EPS, but may involve anticholinergic agents such as procyclidine, benztropine, diphenhydramine, and trihexyphenidyl.
Low testosterone symptoms in men vary widely, especially across different age groups. If you have low testosterone, it can lead to problems with drive, muscle mass levels, fat distribution, bone ...
Men over 40 need to avoid these workout mistakes in order to keep up healthy fitness plans to keep making strength and muscle gains.