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PCP began to emerge as a recreational drug in major cities in the US in the 1960s. [7] In 1978, People magazine and Mike Wallace of the TV news program 60 Minutes called PCP the country's "number one drug problem". Although recreational use of the drug had always been relatively low, it began declining significantly in the 1980s.
Phencyclidine, a hallucinogenic and dissociative recreational drug, also known as angel dust 3-HO-PCP, a designer drug related to phencyclidine; 3-MeO-PCP, a designer drug related to phencyclidine; 4-MeO-PCP, a research chemical related to phencyclidine; Pneumocystis pneumonia, a form of pneumonia caused by the yeast-like fungus Pneumocystis ...
A drug combination chart designed for harm reduction by TripSit [1]. Polysubstance use or multisubstance use is the use of combinations of psychoactive substances with both legal and illegal substances.
4-Methoxyphencyclidine (methoxydine, 4-MeO-PCP) is a dissociative anesthetic drug that has been sold online as a research chemical. The synthesis of 4-MeO-PCP was first reported in 1965 by the Parke-Davis medicinal chemist Victor Maddox. [ 1 ]
PCP itself is composed of three six-membered rings, which can each be substituted by a variety of groups. These are traditionally numbered in the older research as first the cyclohexyl ring, then the phenyl , and finally the piperidine ring, with the different rings represented by prime notation (') next to the number.
Methylenedioxyphencyclidine (3',4'-MD-PCP, MDPCP) is a recreational designer drug with dissociative effects. It is an arylcyclohexylamine derivative, with similar effects to related drugs such as 3-MeO-PCP and 4-MeO-PCP .
Hamilton travels there to study the drug and finds a dark history of medical experimentation. [7] " October 26, 2016 () 2: 2 "A Positive PCP Story — Hamilton travels across the USA meeting with addicts, dealers, chemists, and celebrities to trace the history of PCP from its pharmaceutical origins to its escape onto the streets. [8] "
TCP has slightly different binding properties to PCP, with more affinity for the NMDA receptors, [3] but less affinity for the sigma receptors. [4] Because of its high affinity for the PCP site of the NMDA receptor complex, the 3 H radiolabelled form of TCP is widely used in research into NMDA receptors.