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A definitive diagnosis can only be made if alloantibodies are discovered in the mare's serum or colostrum and are shown to be against the foal's red blood cells. Such tests include crossmatching the mare's serum to washed red blood cells of the foal, which is added to exogenous complement, and is positive if hemolysis occurs.
Hemoglobinemia can be caused by intrinsic or extrinsic factors. When hemoglobinemia is internally caused, it is a result of recessive genetic defects that cause the red blood cells to lyse, letting the hemoglobin spill out of the cell into the blood plasma. In intravascular hemolysis, hemoglobin is released and binds with haptoglobin. This ...
All infected cats require supportive care, including careful fluids, nutritional support, treatment for complications, and often blood transfusion. [11] Cats that survive the infection should be kept indoors as they can be persistent carriers after surviving infection and might indirectly infect other cats after being themselves bitten by a ...
Defective red cell metabolism (as in glucose-6-phosphate dehydrogenase deficiency and pyruvate kinase deficiency). [11] [12] Wilson's disease may infrequently present with hemolytic anemia without due to excessive inorganic copper in blood circulation, which destroys red blood cells (though the mechanism of hemolysis is still unclear). [13]
Ineffective erythropoiesis is an anemia caused by the premature apoptosis of the body's mature red blood cells [49] and subsequent reduction in an adequate production and full maturation of new healthy red blood cells. [50] Macrocytic anemia: Megaloblastic anemia: D51.1, D52.0, D53.1: 29507
Anemia (also spelled anaemia in British English) is a blood disorder in which the blood has a reduced ability to carry oxygen.This can be due to a lower than normal number of red blood cells, a reduction in the amount of hemoglobin available for oxygen transport, or abnormalities in hemoglobin that impair its function.
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