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  2. Major histocompatibility complex - Wikipedia

    en.wikipedia.org/wiki/Major_histocompatibility...

    In MHC class I, any nucleated cell normally presents cytosolic peptides, ... This page was last edited on 12 January 2025, at 16:14 (UTC).

  3. Major histocompatibility complex and sexual selection

    en.wikipedia.org/wiki/Major_histocompatibility...

    MHC-based sexual selection is known to involve olfactory mechanisms in such vertebrate taxa as fish, mice, humans, primates, birds, and reptiles. [1] At its simplest level, humans have long been acquainted with the sense of olfaction for its use in determining the pleasantness or the unpleasantness of one's resources, food, etc.

  4. Histocompatibility - Wikipedia

    en.wikipedia.org/wiki/Histocompatibility

    The discovery of the MHC and role of histocompatibility in transplantation was a combined effort of many scientists in the 20th century. A genetic basis for transplantation rejection was proposed in a 1914 Nature paper by C.C. Little and Ernest Tyyzer, which showed that tumors transplanted between genetically identical mice grew normally, but tumors transplanted between non-identical mice were ...

  5. Major histocompatibility complex, class I-related - Wikipedia

    en.wikipedia.org/wiki/Major_histocompatibility...

    Non-classical MHC class I genes are very often located on the same chromosome (mice chromosome 17, human chromosome 6) and interspaced within the same loci as the classical MHC genes. MR1 is located on another chromosome, the detailed gene analysis revealed that MR1 is a paralog originated by duplication of MHC locus on chromosome 17 (mice).

  6. Human leukocyte antigen - Wikipedia

    en.wikipedia.org/wiki/Human_leukocyte_antigen

    There are three major and two minor MHC class II proteins encoded by the HLA. The genes of the class II combine to form heterodimeric (αβ) protein receptors that are typically expressed on the surface of antigen-presenting cells. Major MHC class II proteins only occur on antigen-presenting cells, B cells, and T cells. [1] HLA-DP

  7. MHC - Wikipedia

    en.wikipedia.org/wiki/MHC

    MHC may refer to: Biology. Major histocompatibility complex, ... This page was last edited on 24 August 2024, at 12:49 (UTC).

  8. MHC restriction - Wikipedia

    en.wikipedia.org/wiki/MHC_restriction

    HLA-A projected away from the cell surface and presenting a peptide sequence. The peptide-MHC complex presents a surface that looks like an altered self to the TCR. [11] The surface consisting of two α helices from the MHC and a bound peptide sequence is projected away from the host cell to the T cells, whose TCRs are projected away from the T cells towards the host cells.

  9. Model of hierarchical complexity - Wikipedia

    en.wikipedia.org/wiki/Model_of_hierarchical...

    The model of hierarchical complexity (MHC) is a formal theory and a mathematical psychology framework for scoring how complex a behavior is. [4] Developed by Michael Lamport Commons and colleagues, [3] it quantifies the order of hierarchical complexity of a task based on mathematical principles of how the information is organized, [5] in terms of information science.