enow.com Web Search

Search results

  1. Results from the WOW.Com Content Network
  2. Flagellin - Wikipedia

    en.wikipedia.org/wiki/Flagellin

    The filament is made up of eleven smaller "protofilaments", nine of which contains flagellin in the L-type shape and the other two in the R-type shape. [6] The helical N-and C-termini of flagellin form the inner core of the flagellin protein, and is responsible for flagellin's ability to polymerize into a filament. The middle residues make up ...

  3. Flagellum - Wikipedia

    en.wikipedia.org/wiki/Flagellum

    A flagellum (/ f l ə ˈ dʒ ɛ l əm /; pl.: flagella) (Latin for 'whip' or 'scourge') is a hair-like appendage that protrudes from certain plant and animal sperm cells, from fungal spores (), and from a wide range of microorganisms to provide motility.

  4. Toll-like receptor 5 - Wikipedia

    en.wikipedia.org/wiki/Toll-like_receptor_5

    Toll-like receptor 5, also known as TLR5, is a protein which in humans is encoded by the TLR5 gene. [5] It is a member of the toll-like receptor (TLR) family. TLR5 is known to recognize bacterial flagellin from invading mobile bacteria. [6]

  5. Pathogen-associated molecular pattern - Wikipedia

    en.wikipedia.org/wiki/Pathogen-associated...

    Flagellin is also another PAMP that is recognized via the constant domain, D1 by TLR5. [7] Despite being a protein, its N- and C-terminal ends are highly conserved, due to its necessity for function of flagella. [8]

  6. Toll-like receptor - Wikipedia

    en.wikipedia.org/wiki/Toll-like_receptor

    The ability of the immune system to recognize molecules that are broadly shared by pathogens is, in part, due to the presence of immune receptors called toll-like receptors (TLRs) that are expressed on the membranes of leukocytes including dendritic cells, macrophages, natural killer cells, cells of the adaptive immunity T cells, and B cells, and non-immune cells (epithelial and endothelial ...

  7. Toll-like receptor 11 - Wikipedia

    en.wikipedia.org/wiki/Toll-like_receptor_11

    In mice, TLR11 has been shown to recognise (bacterial) flagellin and (eukaryotic) profilin present on certain microbes, it helps propagate a host immune response. TLR11 plays a fundamental role in both the innate and adaptive immune responses, through the activation of tumor necrosis factor-alpha , [ 1 ] the interleukin 12 (IL-12) response, [ 2 ...

  8. Evolution of flagella - Wikipedia

    en.wikipedia.org/wiki/Evolution_of_flagella

    All currently known nonflagellar Type III transport systems serve the function of exporting (injecting) toxin into eukaryotic cells. Similarly, flagella grow by exporting flagellin through the flagellar machinery. It is hypothesised that the flagellum evolved from the type three secretory system.

  9. Pattern recognition receptor - Wikipedia

    en.wikipedia.org/wiki/Pattern_recognition_receptor

    Studies have been conducted on TLR11 as well, and it has been shown that it recognizes flagellin and profilin-like proteins in mice. [9] Nonetheless, TLR11 is only a pseudogene in humans without direct function or functional protein expression. Each of the TLR has been shown to interact with a specific PAMP.