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Sertraline is contraindicated in individuals taking monoamine oxidase inhibitors or the antipsychotic pimozide. Sertraline concentrate contains ethanol and is therefore contraindicated with disulfiram. The prescribing information recommends that treatment of the elderly and patients with liver impairment "must be approached with caution".
The knowledge of MAOIs began with the serendipitous discovery that iproniazid was a potent MAO inhibitor (MAOI). [45] Originally intended for the treatment of tuberculosis, in 1952, iproniazid's antidepressant properties were discovered when researchers noted that the depressed patients given iproniazid experienced a relief of their depression.
Toggle Monoamine oxidase inhibitors (MAOIs) subsection. 11.1 Irreversible. 11.1.1 Non-selective. ... Sertraline (Zoloft, Lustral) Discontinued/withdrawn
Sertraline (Zoloft) Paroxetine (Paxil, Pexeva) Fluvoxamine (Luvox) ... This includes monoamine oxidase inhibitors (MAOIs), St. John’s wort and other medications that increase serotonin. It’s ...
Monoamine oxidase inhibitors (MAOIs) have a long and prosperous history as medications for major depressive disorder (MDD). But this type of antidepressant has mostly seen its day. 4 FDA-Approved ...
Monoamine oxidase inhibitors (MAOIs). MAOIs are an older class of antidepressants, primarily used in the 20th century. Because of their side effects and interaction risk, most MAOIs have been ...
Selegiline (Emsam) – monoamine oxidase MAO-B irreversible inhibitor, catecholaminergic activity enhancer, and weak norepineprhine releasing agent (via metabolites) [437] Sertraline (Zoloft; Lustral) – serotonin reuptake inhibitor [438]
Modern SSRIs like Zoloft have a lower risk of side effects than older antidepressants, such as tricyclic antidepressants (TCAs) or monoamine oxidase inhibitors (MAOIs).