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Ointments are more occlusive than aqueous creams, which are more occlusive than lotion. [5] Water loss through the skin is normally about 4–8 g/(m 2 ⋅h). A layer of petrolatum applied to normal skin can reduce that loss by 50–75% for several hours. [4] Oils naturally produced by the human body moisturize through this same mechanism. [2]
Regarding the same topical glucocorticoid, creams are generally more potent than lotions but less effective than ointments. [2] Creams are especially useful in acute inflammation with exudates due to their drying effects. Creams can also be applied to intertriginous areas that are inappropriate for the application of ointments. [2]
Topical steroids are the topical forms of corticosteroids.Topical steroids are the most commonly prescribed topical medications for the treatment of rash and eczema.Topical steroids have anti-inflammatory properties and are classified based on their skin vasoconstrictive abilities. [1]
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