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Primary ciliary dyskinesia (PCD) is a rare, autosomal recessive genetic ciliopathy, that causes defects in the action of cilia lining the upper and lower respiratory tract, sinuses, Eustachian tube, middle ear, fallopian tube, and flagella of sperm cells.
Depending on the type and amount of irritant gas inhaled, victims can experience symptoms ranging from minor respiratory discomfort to acute airway and lung injury and even death. A common response cascade to a variety of irritant gases includes inflammation , edema and epithelial sloughing , which if left untreated can result in scar formation ...
A ciliopathy is any genetic disorder that affects the cellular cilia or the cilia anchoring structures, the basal bodies, [1] or ciliary function. [2] Primary cilia are important in guiding the process of development, so abnormal ciliary function while an embryo is developing can lead to a set of malformations that can occur regardless of the particular genetic problem. [3]
Early diagnosis is important to prevent complications, which include stenosis (narrowing) of the airway, respiratory tract infection, and damage to the lung tissue. Diagnosis involves procedures such as bronchoscopy, radiography, and x-ray computed tomography to visualize the tracheobronchial tree.
The lack of a reliable epidemiological study or ICD-10 code makes it difficult to understand the incidence of ENS. Qualitative feedback from ENTs that treat this disease indicate that the incidence is underestimated but the condition is debilitating for those that have it.
Signs and symptoms of white lung pneumonia can vary based on what caused the illness in the first place, Dr. Ganjian says. However, these are the most common pneumonia symptoms, according to the ...
Bronchiectasis is a disease in which there is permanent enlargement of parts of the airways of the lung. [5] Symptoms typically include a chronic cough with mucus production. [3] Other symptoms include shortness of breath, coughing up blood, and chest pain. [2] Wheezing and nail clubbing may also occur. [2] Those with the disease often get lung ...
Radiation-induced lung injury (RILI) is a general term for damage to the lungs as a result of exposure to ionizing radiation. [1] In general terms, such damage is divided into early inflammatory damage ( radiation pneumonitis ) and later complications of chronic scarring ( radiation fibrosis ).