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Central nervous system fatigue, or central fatigue, is a form of fatigue that is associated with changes in the synaptic concentration of neurotransmitters within the central nervous system (CNS; including the brain and spinal cord) which affects exercise performance and muscle function and cannot be explained by peripheral factors that affect muscle function.
Management of ME/CFS (myalgic encephalomyelitis/chronic fatigue syndrome) focuses on symptoms management, as no treatments that address the root cause of the illness are available. [ 1 ] : 29 Pacing, or regulating one's activities to avoid triggering worse symptoms, is the most common management strategy for post-exertional malaise .
[23]: 564 The classification of ME/CFS as a neurological disease is based on symptoms which indicate a central role of the nervous system. [24] Alternatively, on the basis of abnormalities in immune cells, ME/CFS is sometimes labelled a neuroimmune condition. [25]
The symptoms vary widely, as do the treatments. Central nervous system tumors are the most common forms of pediatric cancer. Brain tumors are the most frequent and have the highest mortality. [4] Some disorders, such as substance addiction, autism, and ADHD may be regarded as CNS disorders, though the classifications are not without dispute.
The central component of fatigue is triggered by an increase of the level of serotonin in the central nervous system. [134] During motor activity, serotonin released in synapses that contact motor neurons promotes muscle contraction. [135] During high level of motor activity, the amount of serotonin released increases and a spillover occurs.
The condition was explained as being a result of exhaustion of the central nervous system's energy reserves, which Beard attributed to modern civilization. Physicians in the Beard school of thought associated neurasthenia with the stresses of urbanization and with stress suffered as a result of the increasingly competitive business environment.
There are many cortical and subcortical structures implicated in urination [54] and MS lesions in various central nervous system structures can cause these kinds of symptoms. Treatment objectives are the alleviation of symptoms of urinary dysfunction, treatment of urinary infections, reduction of complicating factors and the preservation of ...
Inflammatory demyelinating diseases (IDDs), sometimes called Idiopathic (IIDDs) due to the unknown etiology of some of them, are a heterogenous group of demyelinating diseases - conditions that cause damage to myelin, the protective sheath of nerve fibers - that occur against the background of an acute or chronic inflammatory process.
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