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Schnitzler syndrome or Schnitzler's syndrome is a rare disease characterised by onset around middle age of chronic hives (urticaria) and periodic fever, bone and joint pain (sometimes with joint inflammation), weight loss, malaise, fatigue, swollen lymph glands and enlarged spleen and liver. [1] [2]
For instance, if someone is constantly exposed to black flies, for instance, they might experience headaches, fever, swollen lymph nodes and other symptoms of so-called "black fly fever," Frye says.
Lymphadenopathy or adenopathy is a disease of the lymph nodes, in which they are abnormal in size or consistency.Lymphadenopathy of an inflammatory type (the most common type) is lymphadenitis, [1] producing swollen or enlarged lymph nodes.
The presence of an enlarged spleen, and swollen posterior cervical, axillary, and inguinal lymph nodes are the most useful to suspect a diagnosis of infectious mononucleosis. On the other hand, the absence of swollen cervical lymph nodes and fatigue are the most useful to dismiss the idea of infectious mononucleosis as the correct diagnosis.
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Posterior cervical lymph nodes are most commonly affected, however, axillary, inguinal, and epitrochlear lymph node involvement may also occur. [10] Winterbottom's sign, the tell-tale swollen lymph nodes along the back of the neck, may appear. [9] Winterbottom's sign is common in T. b. gambiense infection. [10]
The symptoms change throughout the infection. In the early stage, symptoms are typically either not present or mild and may include fever, swollen lymph nodes, headaches, or swelling at the site of the bite. [1] After four to eight weeks, untreated individuals enter the chronic phase of disease, which in most cases does not result in further ...
The signs and symptoms of Kikuchi disease are fever, enlargement of the lymph nodes (lymphadenopathy), skin rashes, and headache. [7] In sixty to ninety percent of cases, lymphadenopathy presents in the posterior cervical lymph nodes with diameter enlargement typically being between one and two centimeters, but up to seven centimeters has been reported in literature.
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