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2. Thrombocytopenia - Wikipedia

   en.wikipedia.org/wiki/Thrombocytopenia

   Laboratory tests for thrombocytopenia might include full blood count, liver enzymes, kidney function, vitamin B 12 levels, folic acid levels, erythrocyte sedimentation rate, and peripheral blood smear. If the cause for the low platelet count remains unclear, a bone marrow biopsy is usually recommended to differentiate cases of decreased ...

3. Pseudothrombocytopenia - Wikipedia

   en.wikipedia.org/wiki/Pseudothrombocytopenia

   Tests can mistake small clumps of platelets for leukocytes, thus showing a pseudo­leukocytosis in blood counts. [4] Platelet satellitism. Platelet rosetting, or satelliting, around white blood cells can lead to undercounting by automated analyzers. [5] Clotted samples. Coagulation within the sample leads to undercounting, because the analyzer ...

4. Thrombocythemia - Wikipedia

   en.wikipedia.org/wiki/Thrombocythemia

   In hematology, thrombocythemia is a condition of high platelet (thrombocyte) count in the blood. Normal count is in the range of 150 × 10 9 to 450 × 10 9 platelets per liter of blood, [ 1 ] but investigation is typically only considered if the upper limit exceeds 750 × 10 9 /L.

5. Platelet - Wikipedia

   en.wikipedia.org/wiki/Platelet

   Resting platelets maintain active calcium efflux via a cyclic AMP-activated calcium pump. Intracellular calcium concentration determines platelet activation status, as it is the second messenger that drives platelet conformational change and degranulation. Endothelial prostacyclin binds to prostanoid receptors on the surface of resting platelets.

6. Coagulation testing - Wikipedia

   en.wikipedia.org/wiki/Coagulation_testing

   Tests in platelet rich plasma (close to real conditions in the body, but restrictions as to the terms of work), Tests in whole blood (the most adjusted to human physiology; the test can be started immediately; but the least convenient due to terms of blood storage and difficulties of the results' interpretation).

7. Heparin-induced thrombocytopenia - Wikipedia

   en.wikipedia.org/wiki/Heparin-induced...

   This results in platelet activation and the formation of platelet microparticles, which initiate the formation of blood clots; the platelet count falls as a result, leading to thrombocytopenia. [ 1 ] [ 7 ] In addition, the reticuloendothelial system (mostly the spleen) removes the antibody-coated platelets, further contributing to the ...

8. Immune thrombocytopenic purpura - Wikipedia

   en.wikipedia.org/wiki/Immune_thrombocytopenic...

   Diagnosis of ITP involves identifying a low platelet count through a complete blood count, a common blood test. However, since the diagnosis relies on excluding other potential causes of a low platelet count, additional investigations, such as a bone marrow biopsy, may be necessary in certain cases.

9. Hypoprothrombinemia - Wikipedia

   en.wikipedia.org/wiki/Hypoprothrombinemia

   Hypoprothrombinemia can be the result of a genetic defect, may be acquired as the result of another disease process, or may be an adverse effect of medication.For example, 5-10% of patients with systemic lupus erythematosus exhibit acquired hypoprothrombinemia due to the presence of autoantibodies which bind to prothrombin and remove it from the bloodstream (lupus anticoagulant ...