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163 million (2017) [8] Major depressive disorder (MDD), also known as clinical depression, is a mental disorder [9] characterized by at least two weeks of pervasive low mood, low self-esteem, and loss of interest or pleasure in normally enjoyable activities. Introduced by a group of US clinicians in the mid-1970s, [10] the term was adopted by ...
6% (< 60 years old), 20% (> 60 years old) [4] Vitamin B12 deficiency, also known as cobalamin deficiency, is the medical condition in which the blood and tissue have a lower than normal level of vitamin B 12. [5] Symptoms can vary from none to severe. [1] Mild deficiency may have few or absent symptoms. [1]
Vitamin B 6: pyridoxal phosphate (PLP), the active form of B 6, is a cofactor in the dopamine serotonin pathway, a deficiency in vitamin B 6 may cause depressive symptoms. [98] Folate (vitamin B 9) – Vitamin B 12 cobalamin: Low blood plasma and particularly red cell folate and diminished levels of vitamin B 12 have been found in patients with ...
Depression affects around 14.8 million adults in the U.S. That?s around 7 percent of the entire population aged 18 and over.
Biology of depression. Scientific studies have found that different brain areas show altered activity in humans with major depressive disorder (MDD), [1] and this has encouraged advocates of various theories that seek to identify a biochemical origin of the disease, as opposed to theories that emphasize psychological or situational causes.
Endocrinology. Vitamin deficiency is the condition of a long-term lack of a vitamin. When caused by not enough vitamin intake it is classified as a primary deficiency, whereas when due to an underlying disorder such as malabsorption it is called a secondary deficiency. An underlying disorder can have 2 main causes:
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