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The test was once part of the World Health Organization (WHO) algorithm for diagnosis of dengue fever, [3] however it is no longer used in the latest WHO guidance. [4] Studies have shown that the tourniquet test has low predictive value for dengue fever and should be used in conjunction with other tests for a reliable diagnosis. [5] [6] [7] [8]
The Hess test or Rumpel-Leede test is a medical test used to assess capillary fragility. [1] It is also called the Tourniquet test . To perform the test, pressure is applied to the forearm with a blood pressure cuff inflated to between systolic and diastolic blood pressure for 10 minutes.
Reference ranges (reference intervals) for blood tests are sets of values used by a health professional to interpret a set of medical test results from blood samples. Reference ranges for blood tests are studied within the field of clinical chemistry (also known as "clinical biochemistry", "chemical pathology" or "pure blood chemistry"), the ...
Severe dengue can develop suddenly, sometimes after a few days as the fever subsides. [24] Leakage of plasma from the capillaries results in extreme low blood pressure and hypovolemic shock; Patients with severe plasma leakage may have fluid accumulation in the lungs or abdomen, insufficient protein in the blood, or thickening of the blood ...
Most dengue fever patients recover in a week, but in severe cases the disease can be life-threatening and require hospitalization since it can result in shock, internal bleeding and even death.
The tourniquet test, which is particularly useful in settings where no laboratory investigations are readily available, involves the application of a blood pressure cuff at between the diastolic and systolic pressure for five minutes, followed by the counting of any petechial hemorrhages; a higher number makes a diagnosis of dengue more likely.
Hormone-sensitive lipase, which has 11-fold greater affinity for diglycerides than triglycerides, predominantly cleaves these diglycerides, forming 2-monoglyceride and a free fatty acid. [14] [15] HSL is activated when the body needs to mobilize energy stores, and so responds positively to catecholamines and ACTH. It is inhibited by insulin.
The reference ranges for the complete blood count represent the range of results found in 95% of apparently healthy people. [note 2] [35] By definition, 5% of results will always fall outside this range, so some abnormal results may reflect natural variation rather than signifying a medical issue. [36]