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The activation-synthesis hypothesis, proposed by Harvard University psychiatrists John Allan Hobson and Robert McCarley, is a neurobiological theory of dreams first published in the American Journal of Psychiatry in December 1977.
In 1977, Hobson and McCarley developed the activation synthesis theory of dreaming that said that dreams do not have meanings and are the result of the brain attempting to make sense of random neuronal firing in the cortex. [2] McCarley has extensively studied the brainstem mechanisms that control REM sleep. [3]
The Crick-Mitchison theory is a variant upon Hobson and McCarley's activation-synthesis hypothesis, [4] published in December 1977. Hobson and McCarley hypothesized that a brain stem neuronal mechanism sends pontine-geniculo-occipital (or PGO) waves that automatically activate the mammalian forebrain. By comparing information generated in ...
The mediaeval great chain of being as a staircase, implying the possibility of progress: [1] Ramon Lull's Ladder of Ascent and Descent of the Mind, 1305. Alternatives to Darwinian evolution have been proposed by scholars investigating biology to explain signs of evolution and the relatedness of different groups of living things.
John Allan Hobson (June 3, 1933 – July 7, 2021 [1]) was an American psychiatrist and dream researcher. He was known for his research on rapid eye movement sleep.He was Professor of Psychiatry, Emeritus, Harvard Medical School, and Professor, Department of Psychiatry, Beth Israel Deaconess Medical Center.
[a] Clonal selection theory (CST): hematopoietic stem cells (1) differentiate and undergo genetic rearrangement to produce a population of cells possessing a wide range of pre-existing diversity with respect to antibody expression (2). Lymphocytes expressing antibodies that would lead to autoimmunity are filtered from the population (3), while ...
The original, modern synthesis view of population genetics assumes that mutations provide ample raw material, and focuses only on the change in frequency of alleles within populations. [13] The main processes influencing allele frequencies are natural selection , genetic drift , gene flow and recurrent mutation .
The modern synthesis [a] was the early 20th-century synthesis of Charles Darwin's theory of evolution and Gregor Mendel's ideas on heredity into a joint mathematical framework. Julian Huxley coined the term in his 1942 book, Evolution: The Modern Synthesis .