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Solitary rectal ulcer syndrome (SRUS) is a rare benign disease characterized by symptoms, clinical findings, and histological abnormalities. [9] Only 40% of patients have ulcers; 20% of patients have a single ulcer, and the remaining lesions range in size and form from broad-based polypoid to hyperemic mucosa. [10]
The cause of UC is unknown. [1] Theories involve immune system dysfunction , genetics , changes in the normal gut bacteria , and environmental factors. [ 1 ] [ 8 ] Rates tend to be higher in the developed world with some proposing this to be the result of less exposure to intestinal infections , or to a Western diet and lifestyle.
According to one report, constipation is present in about 55% of cases, but diarrhea is present in 20%–40% of cases. [1] Reported symptoms are: Hematochezia (lower gastrointestinal bleeding). [5] which can vary from minor to severe. [3] Rectal pain. [3] Pelvic discomfort. [3] Tenesmus. [3] Sensation of incomplete evacuation of stool. [3]
Management of ulcerative colitis involves first treating the acute symptoms of the disease, then maintaining remission. Ulcerative colitis is a form of colitis, a disease of the intestine, specifically the large intestine or colon, that includes characteristic ulcers, or open sores, in the colon.
Constipation may result from lifestyle factors, impaction of a rigid stool in the rectum, or in neonates, Hirschprung's disease. [5]: 913–915 Diseases affecting the large intestine may cause blood to be passed with stool, may cause constipation, or may result in abdominal pain or a fever.
Stercoral ulcer is an ulcer of the colon due to pressure and irritation resulting from severe, prolonged constipation due to a large bowel obstruction, damage to the autonomic nervous system, or stercoral colitis. It is most commonly located in the sigmoid colon and rectum.
A new study has suggested that damage to the upper gastrointestinal tract from conditions such as reflux, peptic ulcers, and prolonged use of NSAIDS may increase Parkinson’s risk by 76%.
First, the excessive bacterial concentrations can cause direct inflammation of the small bowel cells, leading to an inflammatory diarrhea. The malabsorption of lipids, proteins and carbohydrates may cause poorly digestible products to enter into the colon. This can cause an osmotic diarrhea or stimulate the colonic cells to cause a secretory ...
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