Search results
Results from the WOW.Com Content Network
A photolabile protecting group (PPG; also known as: photoremovable, photosensitive, or photocleavable protecting group) is a chemical modification to a molecule that can be removed with light. PPGs enable high degrees of chemoselectivity as they allow researchers to control spatial, temporal and concentration variables with light.
Chemical components cartoon of a TIVA tag before photoactivation. "PL" refers to a photocleavable linker and "CPP" refers to a cell-penetrating peptide. A transcriptome in vivo analysis tag (TIVA tag) is a multifunctional, photoactivatable mRNA-capture molecule designed for isolating mRNA from a single cell in complex tissues.
The activation can be either irreversible, as in the case of caged peptides with photocleavable protecting groups, [1] or reversible, utilizing molecular photoswitches like azobenzenes or diarylethenes, [2] [3] [4] and diarylethenes [5] [6] By incorporating these light-responsive components into the peptide structure, peptide properties ...
Nucleic acids play important roles as cellular information storage and gene regulation machinery. In efforts to regulate this machinery by light, DNA and RNA have been modified with photocleavable groups at the backbone (in an approach called ‘statistical backbone caging’; the protection groups react mainly with backbone phosphate groups).
Upon visible light irradiation and in the presence of ammonium persulfate (APS), Ru 2+ enters its excited state and is oxidized to Ru 3+. [4] Ru 3+ is now an extremely reactive oxidizer that only wants to accept one electron instead of the standard two. [ 4 ]
WASHINGTON (Reuters) -Hundreds of internal contractors working for the U.S. Agency for International Development are being put on unpaid leave and some are being terminated after U.S. President ...
Smoothies are a fantastic way to get a powerful punch of nutrients. But, despite being packed with antioxidant-rich fruits and vegetables, many smoothies lack one key macronutrient that can help ...
Opsins without the lysine are not light sensitive, [42] [43] [44] including rhodopsin. Rhodopsin is made constitutively (continuously) active by some of those mutations even without light. [45] [46] [47] Also wild-type rhodopsin is constitutively active, if no 11-cis-retinal is bound, but much less. [48] Therefore 11-cis-retinal is an inverse ...