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As an American legal term, narcotic refers to cocaine and opioids, and their source materials; it is also loosely applied to any illegal or controlled psychoactive drug. [28] [29] In some jurisdictions all controlled drugs are legally classified as narcotics. The term can have pejorative connotations and its use is generally discouraged where ...
Common side effects include dizziness, sleepiness, nausea, itchiness, and constipation. [7] Serious side effects may include abuse, low blood pressure, seizures, respiratory depression, and serotonin syndrome. [7] Rapidly decreasing the dose may result in opioid withdrawal. [7] Generally, use during pregnancy or breastfeeding is not recommended ...
Carbonate derivatives of 14β-hydroxycodeine "viz., 14β-hydroxy-6-O-(methoxycarbonyl)codeine, 6-O-methoxycarbonyl-14β-(methoxycarbonyloxy)codeine, and 14β-acetoxy-6-O-methoxy-carbonylcodeine, potential substrates for ring C modification in morphinane (sic) alkaloids, were synthesized for the first time."
Chlorthalidone is the thiazide drug that is most strongly supported by the evidence as providing a mortality benefit; in the ALLHAT study, a chlorthalidone dose of 12.5 mg was used, with titration up to 25 mg for those subjects who did not achieve blood pressure control at 12.5 mg. Chlorthalidone has repeatedly been found to have a stronger ...
In 2011, it was the leading cause of drug-related deaths in the U.S. [57] However, from 2012 onwards, heroin and fentanyl have become more common causes of drug-related deaths. [ 57 ] Oxycodone overdose has also been described to cause spinal cord infarction in high doses and ischemic damage to the brain , due to prolonged hypoxia from ...
High blood pressure, also called hypertension, is a vicious and smart adversary.It’s vicious because it greatly increases the odds of heart disease and stroke, some of the leading causes of ...
Common adverse effects of bupropion with the greatest difference from placebo are dry mouth, nausea, constipation, insomnia, anxiety, tremor, and excessive sweating. [10] [11] Raised blood pressure is notable. [23] Rare but serious side effects include seizures, [10] [11] liver toxicity, [24] psychosis, [25] and risk of overdose. [26]
[10] [14] Hydrocodone is a controlled drug: in the United States, it is classified as a Schedule II Controlled Substance. Common side effects include dizziness, sleepiness, nausea, and constipation. [10] Serious side effects may include low blood pressure, seizures, QT prolongation, respiratory depression, and serotonin syndrome. [10]
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