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A patient is said to have diastolic dysfunction if they have signs and symptoms of heart failure but the left ventricular ejection fraction is normal. A second approach is to use an elevated BNP level in the presence of normal ejection fraction to diagnose diastolic heart failure. Concordance of both volumetric and biochemical measurements and ...
Heart failure (HF), also known as congestive heart failure (CHF), is a syndrome caused by an impairment in the heart's ability to fill with and pump blood.. Although symptoms vary based on which side of the heart is affected, HF typically presents with shortness of breath, excessive fatigue, and bilateral leg swelling. [3]
Defects in cellular processes such as autophagy and mitophagy are thought to contribute to the development of diabetic cardiomyopathy. [2] Diabetic cardiomyopathy is characterized functionally by ventricular dilation, enlargement of heart cells, prominent interstitial fibrosis and decreased or preserved systolic function [5] in the presence of a diastolic dysfunction.
Signs and symptoms of heart failure. The symptoms of heart failure tend to be the same whether or not a person has diabetes. Fatigue lands at or near the top of the list, although at first this ...
Symptoms commonly documented in patients history, classified according to cause: [2] [5] [6] [8] [9] Neurological - Dizziness, near syncope, and confusion. Heart failure - Dyspnea, orthopnea, paroxysmal nocturnal dyspnea, and edema. Hypotension - Seizure, mental status change, diaphoresis, and signs of orthostatic hypotension and shock.
The reversal of the E/A ratio ('A' velocity becomes greater than 'E' velocity) is often accepted as a clinical marker of diastolic dysfunction, in which the left ventricular wall becomes so stiff as to impair proper filling, which can lead to diastolic heart failure. This can occur, for instance, with longstanding untreated hypertension.
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