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Korsakoff syndrome (KS) [1] is a disorder of the central nervous system characterized by amnesia, deficits in explicit memory, and confabulation. This neurological disorder is caused by a deficiency of thiamine (vitamin B 1 ) in the brain, and it is typically associated with and exacerbated by the prolonged, excessive ingestion of alcohol . [ 2 ]
Wernicke-Korsakoff syndrome ( WKS) is the combined presence of Wernicke encephalopathy (WE) and alcoholic Korsakoff syndrome (AKS [clarification needed] ). Due to the close relationship between these two disorders, people with either are usually diagnosed with WKS as a single syndrome. It mainly causes vision changes, ataxia and impaired memory ...
Most presentations of alcohol dementia are somewhere along the spectrum between a global dementia and Korsakoff's psychosis, and may include symptoms of both. [2] Individuals affected by alcohol-related dementia may develop memory problems, language impairment, and an inability to perform complex motor tasks such as getting dressed.
Wernicke encephalopathy ( WE ), also Wernicke's encephalopathy, [ 1] or wet brain is the presence of neurological symptoms caused by biochemical lesions of the central nervous system after exhaustion of B-vitamin reserves, in particular thiamine (vitamin B 1 ). [ 2] The condition is part of a larger group of thiamine deficiency disorders that ...
Sergei Sergeyevich Korsakov ( Russian: Серге́й Серге́евич Ко́рсаков; 22 January 1854, Gus-Khrustalny – 1 May 1900, Moscow) was a neuropsychiatrist from the Russian Empire, known for his studies on alcoholic psychosis. His name is lent to the eponymous Korsakov's syndrome and Wernicke–Korsakoff syndrome .
Psychosis is a condition of the mind or psyche that results in difficulties determining what is real and what is not real. [ 3] Symptoms may include delusions and hallucinations, among other features. [ 3] Additional symptoms are incoherent speech and behavior that is inappropriate for a given situation. [ 3]
Korsakoff's patients who confabulate are more likely than healthy adults to falsely recognize distractor words, suggesting that false recognition is a "confabulatory behavior." Alzheimer's disease is a condition with both neurological and psychological components. It is a form of dementia associated with severe frontal lobe dysfunction.
The brain is a major target for the actions of alcohol, and heavy alcohol consumption has long been associated with brain damage. Studies clearly indicate that alcohol is neurotoxic, with direct effects on nerve cells. Chronic alcohol abusers are at additional risk for brain injury from related causes, such as poor nutrition, liver disease, and ...