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  2. Tissue-type plasminogen activator - Wikipedia

    en.wikipedia.org/wiki/Tissue-type_plasminogen...

    5327 18791 Ensembl ENSG00000104368 ENSMUSG00000031538 UniProt P00750 P11214 RefSeq (mRNA) NM_033011 NM_000930 NM_000931 NM_001319189 NM_008872 RefSeq (protein) NP_000921 NP_001306118 NP_127509 NP_032898 Location (UCSC) Chr 8: 42.17 – 42.21 Mb Chr 8: 23.25 – 23.27 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Tissue-type plasminogen activator, short name tPA, is a protein that ...

  3. Alteplase - Wikipedia

    en.wikipedia.org/wiki/Alteplase

    Alteplase, sold under the brand name Activase among others, is a biosynthetic form of human tissue-type plasminogen activator (t-PA). It is a thrombolytic medication used to treat acute ischemic stroke, acute ST-elevation myocardial infarction (a type of heart attack), pulmonary embolism associated with low blood pressure, and blocked central venous catheter. [5]

  4. Cerebroprotectant - Wikipedia

    en.wikipedia.org/wiki/Cerebroprotectant

    A cerebroprotectant (formerly known as a neuroprotectant) is a drug that is intended to protect the brain after the onset of acute ischemic stroke. [1] As stroke is the second largest cause of death worldwide and a leading cause of adult disability, over 150 drugs have been tested in clinical trials to provide cerebroprotection.

  5. National Institutes of Health Stroke Scale - Wikipedia

    en.wikipedia.org/wiki/National_Institutes_of...

    Current standards recommend for tPA to be delivered within 4,5 hours of onset, while best results occur when treatment is delivered within 90 minutes of onset. [15] Since the NIHSS has been established as a quick and consistent quantifier of stroke severity, many physicians have looked to NIHSS scores as indicators for tPA treatment. [16]

  6. When it comes to stroke, time and treatment are key - AOL

    www.aol.com/news/comes-stroke-time-treatment-key...

    Each year, nearly 800,000 people suffer a stroke in the United States. That’s about one stroke every 40 seconds. When it comes to stroke, time and treatment are key

  7. Plasminogen activator - Wikipedia

    en.wikipedia.org/wiki/Plasminogen_activator

    5340 18815 Ensembl ENSG00000122194 ENSMUSG00000059481 UniProt P00747 P20918 RefSeq (mRNA) NM_001168338 NM_000301 NM_008877 RefSeq (protein) NP_000292 NP_001161810 NP_032903 Location (UCSC) Chr 6: 160.7 – 160.75 Mb Chr 17: 12.6 – 12.64 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Plasminogen activator inhibitor-1 not only functions as an inhibitor, but other roles of PAI-1 ...

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