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They can include low blood cell counts, vomiting, loss of appetite, diarrhea, hair loss, and fever. [2] Other severe side effects include allergic reactions and low blood pressure. [2] [4] Use during pregnancy will likely harm the fetus. [2] Etoposide is in the topoisomerase inhibitor family of medication. [2] It is believed to work by damaging ...
Pancytopenia is a medical condition in which there is significant reduction in the number of almost all blood cells (red blood cells, white blood cells, platelets, monocytes, lymphocytes, etc.). If only two parameters from the complete blood count are low, the term bicytopenia can be used. The diagnostic approach is the same as for pancytopenia.
Hyperphosphatemia causes acute kidney injury in tumor lysis syndrome, because of deposition of calcium phosphate crystals in the kidney parenchyma. [2] Hypocalcemia. Because of the hyperphosphatemia, calcium is precipitated to form calcium phosphate, leading to hypocalcemia. [2] Symptoms of hypocalcemia include (but are not limited to): [9] tetany
The decrease in blood cell counts does not occur right at the start of chemotherapy because the drugs do not destroy the cells already in the bloodstream (these are not dividing rapidly). Instead, the drugs affect new blood cells that are being made by the bone marrow. [4] When myelosuppression is severe, it is called myeloablation. [5]
Hypotension, also known as low blood pressure, is a cardiovascular condition characterized by abnormally reduced blood pressure. [1] Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood [2] and is indicated by two numbers, the systolic blood pressure (the top number) and the diastolic blood pressure (the bottom number), which are the ...
The chemotherapy drug 5-FU can be toxic to some people with cancer. A quick, cheap test can show if chemo is safe for a patient, but few doctors order it. A quick, cheap test could protect against ...
Blood growth factors are medicines that stimulate the bone marrow to produce more of a certain kind of blood cell. Commonly used examples include G-CSF and erythropoietin. These drugs are sometimes used with ABVD to prevent neutropenia (low white blood cell count) and anemia related to the chemotherapy, although their use is not universal.
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