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A Therac-25 had been in operation for six months in Marietta, Georgia at the Kennestone Regional Oncology Center when, on June 3, 1985, applied radiation therapy treatment following a lumpectomy was being performed on 61-year-old woman Katie Yarbrough.
Between 1985 and 1987, a series of design flaws in AECL's Therac-25 medical accelerator caused massive overdoses of radiation [18] on 6 different occasions, resulting in five deaths. In 1987 the machine was found defective by the Food and Drug Administration (FDA) and eventually recalled by AECL despite their multiple denials that the problems ...
Therac-25 Incidents [ edit ] Yakima Valley Memorial Hospital was the site of two clinical radiotherapy incidents, wherein hospital staff used a Therac-25 machine to treat cancer patients. [ 12 ]
Therac-25 used a 25 MeV electron beam to produce an X-ray for treatment. 25 MeV is 25 million electron volts (eV -- an eV is the energy needed to move one electron through a potential of one volt). Image A simulated cross section view of radiation dispersing upon entering the body [A simulated cross section view of radiation dispersing upon ...
However, mistakes do occasionally occur; for example, the radiation therapy machine Therac-25 was responsible for at least six accidents between 1985 and 1987, where patients were given up to one hundred times the intended dose; two people were killed directly by the radiation overdoses.
There are exceptions, such as the Therac-25 accidents and the 1958 Cecil Kelley criticality accident, where the absorbed doses in Gy or rad are the only useful quantities, because of the targeted nature of the exposure to the body. Radiotherapy treatments are typically prescribed in terms of the local absorbed dose, which might be 60 Gy or higher.
The 2015 update of guidelines of the Association of Gynecological Oncology (AGO), an autonomous community of the German Society of Gynecology and Obstetrics (DGGG) and the German Cancer Society includes TARGIT IORT during lumpectomy as a recommended option for women with a T1, Grade 1 or 2, ER positive breast cancer.
Therac 25: Dora Award Nominee for Best New Play. 2000 Zadie's Shoes: Dora Award Nominee for Best New Play. 2002 Sunday Father: Dora Award Nominee for Best New Play. Misha: One Act Play The Tragic Role: Adaptation of Anton Chekhov's play for Soulpepper Theatre. 2003 Mosley and Me: 2006 Rattle the Bones: 2009 Parfumerie