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Piperazine is present in prazosin, terazosin and doxazosin which seems to contribute to the non-selective inhibition of alpha-1 receptors. [50] Comparison between prazosin, terazosin, and alfuzosin. The conversion of the furan ring to a tetrahydrofuran ring (colored purple) contributed to an increase in half-life of terazosin.
Alternative alpha blockers, such as prazosin, tamsulosin, doxazosin, or terazosin can have adverse interactions with beta blockers, erectile dysfunction drugs, anxiolytics, and antihistamines. [2] Again, these interactions can cause dangerous hypotension .
Other drugs of the same family, doxazosin (Cardura) and terazosin (Hytrin), can also cause this phenomenon, though less frequently. The cause is not clear. It occurs more commonly in patients who are salt and fluid volume depleted (as happens due to the use of diuretics), or were using beta blockers. [4]
Doxazosin, sold under the brand name Cardura among others, is a medication used to treat symptoms of benign prostatic hyperplasia (enlarged prostate), ...
Terazosin, sold under the brand name Hytrin among others, is a medication used to treat symptoms of an enlarged prostate and high blood pressure. [1] For high blood pressure, it is a less preferred option. [1] It is taken by mouth. [1] Common side effects include dizziness, headache, feeling tired, swelling, nausea, and low blood pressure with ...
Bradley Dawson is escorted through Lautoka High Court in Suva, Fiji, on Jan. 27, 2025. Dawson was convicted in the murder of his wife, Christie Chen, on their honeymoon in 2023.
Defense Secretary Pete Hegseth ordered an immediate pause on gender-affirming medical care procedures for all active-duty service members in a memo that was addressed to senior Pentagon leadership ...
Alpha-blockers, including prazosin, terazosin, doxazosin, or tamsulosin, do not appear to affect all-cause mortality in heart failure rehospitalization in those also receiving β-blockers. [23] Tamsulosin can also cause retrograde ejaculation, which occurs when semen is redirected to the urinary bladder instead of being ejaculated normally.