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  2. Familial renal disease in animals - Wikipedia

    en.wikipedia.org/wiki/Familial_renal_disease_in...

    Samoyeds can be affected by basement membrane disease of the kidneys. It is inherited through the X chromosome and is therefore more severe in affected male dogs. Findings in male dogs include the presence of protein and glucose in the urine and the inability to concentrate urine, and progression to kidney failure by the age of 9 months and death by 16 months. [3]

  3. Creatinine - Wikipedia

    en.wikipedia.org/wiki/Creatinine

    Serum creatinine (a blood measurement) is an important indicator of kidney function, because it is an easily measured byproduct of muscle metabolism that is excreted unchanged by the kidneys. Creatinine itself is produced [ 5 ] via a biological system involving creatine , phosphocreatine (also known as creatine phosphate), and adenosine ...

  4. Grape toxicity in dogs - Wikipedia

    en.wikipedia.org/wiki/Grape_toxicity_in_dogs

    The reason some dogs develop kidney failure following ingestion of grapes and raisins is not known. [3] Types of grapes involved include both seedless and seeded, store-bought and homegrown, and grape pressings from wineries. [4] A mycotoxin is suspected to be involved, but none has been found in grapes or raisins ingested by affected dogs. [5]

  5. Assessment of kidney function - Wikipedia

    en.wikipedia.org/wiki/Assessment_of_kidney_function

    The GFR, however, does not reveal the source of the kidney disease. This is accomplished by urinalysis, measurement of urine protein excretion, kidney imaging, and, if necessary, kidney biopsy. [1] Much of renal physiology is studied at the level of the nephron – the smallest functional unit of the kidney

  6. Chronic kidney disease - Wikipedia

    en.wikipedia.org/wiki/Chronic_kidney_disease

    Diagnosis of CKD is largely based on history, examination, and urine dipstick combined with the measurement of the serum creatinine level. Differentiating CKD from acute kidney injury (AKI) is important because AKI can be reversible. One diagnostic clue that helps differentiate CKD from AKI is a gradual rise in serum creatinine (over several ...

  7. Azotemia - Wikipedia

    en.wikipedia.org/wiki/Azotemia

    Azotemia (from azot 'nitrogen' and -emia 'blood condition'), also spelled azotaemia, is a medical condition characterized by abnormally high levels of nitrogen-containing compounds (such as urea, creatinine, various body waste compounds, and other nitrogen-rich compounds) in the blood.

  8. Dog health - Wikipedia

    en.wikipedia.org/wiki/Dog_health

    Grapes and raisins can cause acute kidney failure in dogs [40] The exact mechanism is unknown, nor is there any means to determine the susceptibility of an individual dog. While as little as one raisin can be toxic to a susceptible 10 pounds (4.5 kg) dog, some other dogs have eaten as much as a pound of grapes or raisins at a time without ill ...

  9. Protein toxicity - Wikipedia

    en.wikipedia.org/wiki/Protein_toxicity

    Increased creatinine levels in the blood can also be a sign of kidney damage and inability to excrete protein waste by-products properly. A confirmation of kidney disease or kidney failure is often obtained by performing a blood test which measures the concentration of creatinine and urea (blood urea nitrogen). [23]

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