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Fluorouracil (5-FU) is a skin cream or solution that treats skin cancer. It’s a chemotherapy agent that destroys cancer cells. Follow the instructions on the label to safely apply this cream or solution on your skin.
For topical dosage form (cream and solution): For actinic or solar keratosis: Adults—Apply to the affected area 2 times a day for 2 to 4 weeks. Children—Use and dose must be determined by your doctor. For superficial basal cell carcinomas: Adults—Apply to the affected area 2 times a day for 3 to 6 weeks.
Fluorouracil (Topical. This information from Lexicomp explains what you need to know about this medication, including what it’s used for, how to take it, its side effects, and when to call your healthcare provider.
5% cream or solution: Apply 2 times a day in an amount sufficient to cover the lesions; continue until the inflammatory response reaches the erosion stage, then discontinue use. Duration of therapy: 3 to 6 weeks; however, therapy may be required for as long as 10 to 12 weeks before lesions are obliterated. Comments:
Topical fluorouracil is available as Carac, Efudex, Tolak, and generic topical fluorouracil in the following dosage forms that are applied to the skin. 0.5% topical cream. 4% topical cream....
Combination cream instructions: 1. Clean the area with soap and water before applying the medicine. The treatment is more effective if you scrub away any crust or flakes with a washcloth. 2. After washing the area, apply a thin layer of medicine to the treatment site with your fingertips, then wash your hands after application.
Fluorouracil topical dosing information. Usual Adult Dose for Keratosis: 0.5% cream (microsphere formulation): Apply to the affected area once a day where actinic keratosis lesions appear, using enough to cover the entire area with a thin film.