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  2. Genotype frequency - Wikipedia

    en.wikipedia.org/wiki/Genotype_frequency

    Genotype frequency in a population is the number of individuals with a given genotype divided by the total number of individuals in the population. [2] In population genetics, the genotype frequency is the frequency or proportion (i.e., 0 < f < 1) of genotypes in a population. Although allele and genotype frequencies are related, it is ...

  3. Hardy–Weinberg principle - Wikipedia

    en.wikipedia.org/wiki/Hardy–Weinberg_principle

    Each line shows one of the three possible genotypes. In population genetics, the Hardy–Weinberg principle, also known as the Hardy–Weinberg equilibrium, model, theorem, or law, states that allele and genotype frequencies in a population will remain constant from generation to generation in the absence of other evolutionary influences.

  4. Balancing selection - Wikipedia

    en.wikipedia.org/wiki/Balancing_selection

    Balancing selection refers to a number of selective processes by which multiple alleles (different versions of a gene) are actively maintained in the gene pool of a population at frequencies larger than expected from genetic drift alone. Balancing selection is rare compared to purifying selection. [1] It can occur by various mechanisms, in ...

  5. Population structure (genetics) - Wikipedia

    en.wikipedia.org/wiki/Population_structure...

    Population structure (also called genetic structure and population stratification) is the presence of a systematic difference in allele frequencies between subpopulations. In a randomly mating (or panmictic) population, allele frequencies are expected to be roughly similar between groups. However, mating tends to be non-random to some degree ...

  6. Heterozygote advantage - Wikipedia

    en.wikipedia.org/wiki/Heterozygote_advantage

    Heterozygote advantage is a major underlying mechanism for heterosis, or "hybrid vigor", which is the improved or increased function of any biological quality in a hybrid offspring. Previous research, comparing measures of dominance, overdominance and epistasis (mostly in plants), found that the majority of cases of heterozygote advantage were ...

  7. Epigenetics in learning and memory - Wikipedia

    en.wikipedia.org/wiki/Epigenetics_in_learning...

    Miller and Sweatt demonstrated that rats trained in a contextual fear conditioning paradigm had elevated levels of mRNA for DNMT3a and DNMT3b in the hippocampus. [4] Fear conditioning is an associative memory task where a context, like a room, is paired with an aversive stimulus, like a foot shock; animals who have learned the association show higher levels of freezing behavior when exposed to ...

  8. Quantitative genetics - Wikipedia

    en.wikipedia.org/wiki/Quantitative_genetics

    Also note that σ 2 D < σ 2 d ("2pq" being always a fraction); and note that (1) σ 2 D = 2pq σ 2 d, and that (2) σ 2 d = σ 2 D / (2pq). That is: it is confirmed that σ 2 D does not quantify the dominance variance in the model. It is σ 2 d which does that. However, the dominance variance (σ 2 d) can be estimated readily from the σ 2 D ...

  9. Duplex locomotive - Wikipedia

    en.wikipedia.org/wiki/Duplex_locomotive

    In operation, the Q2 could outperform pre-existing freight engines hauling double the tonnage of their predecessors. Furthermore, the Q2 had no problems building up steam power and was known to be a very smooth-riding engine. 26 were built at PRR's Altoona Works, and they were by far the most successful duplex type. The duplex propensity to ...

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