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Selection criteria included blood glucose > 250 mg/dL, anion gap > 10, ketones as determined by beta-hydroxybutyrate ≥ 0.6 mmol/L, and available urine toxicology screening on admission.
When the anion gap is increased (≥16) with a normal chloride level, the acidosis is from excess acid production. Metabolic acidosis is a common finding in the sick newborn. In some cases, the ...
[44,145] The normal anion gap has been historically reported to be 12 mEq/l, and values >14-15 mEq/l have been considered to indicate the presence of an increased anion gap metabolic acidosis.
Topiramate is known to cause an imbalance in serum bicarbonate and chloride levels due to its inhibitory effect on carbonate dehydratase. Although hyperchloremic metabolic acidosis due to ...
One of the known consequences of sodium thiosulfate administration is an elevation in the anion gap, which is explained by the dissociation of the molecule into thiosulfuric acid. Not explained is ...
The anion gap calculation is useful to distinguish among the different causes of metabolic acidosis: Anion gap = (Na) - (bicarbonate [HCO3] + chloride) Normal anion gap = 6-12 mEq
The anion gap was high at 26 mmol/L and bicarbonate was low at 8 mmol/L. Urine analysis confirmed ketonuria. She was admitted to the ICU and given an infusion of dextrose and sodium bicarbonate ...
Summary: A 37-year-old man hospitalized for mental status changes and possible seizure developed hyperchloremic, normal anion-gap, metabolic acidosis. His medical history was significant for AIDS ...
After receiving increased dosages of topiramate, a 37-year-old man developed hyperchloremic, normal anion-gap, metabolic acidosis, which resolved after discontinuation of the drug.
Metabolic acidosis was reported in a 20-year-old man taking topiramate 400 mg daily for nine months, in addition to phenytoin and valproic acid for a seizure disorder. [8] The patient had acute ...