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  2. Tadalafil: Your Ultimate Guide to Dosages, Side Effects & More

    www.aol.com/tadalafil-ultimate-guide-dosages...

    Tadalafil is available in several dosages, from a minimum dosage of 2.5mg (milligrams) all the way up to a 20mg per tablet, the maximum dose of tadalafil in 24 hours. Tadalafil 10mg: Typical ...

  3. Cialis Side Effects: What to Expect (& How to Avoid Them) - AOL

    www.aol.com/cialis-side-effects-expect-avoid...

    Tadalafil side effects aren’t the only concern when taking this drug. As mentioned, Cialis can interact with other PDE5 inhibitors for ED, as well as medications prescribed to treat hypertension ...

  4. Is It Safe to Take Cialis Daily? - AOL

    www.aol.com/safe-cialis-daily-115900442.html

    What is Cialis (Tadalafil)? Like other ED medications, Cialis is a PDE5 inhibitor.It works by blocking the effects of PDE5, or cGMP-specific phosphodiesterase type 5 — an enzyme that’s ...

  5. Tadalafil - Wikipedia

    en.wikipedia.org/wiki/Tadalafil

    Tadalafil, sold under the brand name Cialis among others, is a medication used to treat erectile dysfunction, benign prostatic hyperplasia, and pulmonary arterial hypertension. [ 5 ] [ 6 ] [ 8 ] It is taken by mouth . [ 8 ]

  6. PDE5 inhibitor - Wikipedia

    en.wikipedia.org/wiki/PDE5_inhibitor

    PDE5 inhibitors are contraindicated within 24 hours (or 48 hours with tadalafil) of taking alpha-blockers, soluble guanylate cyclase stimulators, or nitrate medications such as isosorbide mononitrate or isosorbide dinitrate. [1] Concurrent use of these medications can lead to life-threatening low blood pressure. [5]

  7. Discovery and development of phosphodiesterase 5 inhibitors

    en.wikipedia.org/wiki/Discovery_and_development...

    This allows for a longer therapeutic window and is therefore often a more convenient drug than others with a shorter therapeutic window. Tadalafil is more bioavailable (80%) than sildenafil (40%) and vardenafil (15%) but it has a slow absorption, or about 2 hours compared to 50 minutes of sildenfil. Vardenafil is most known for its potency. [24]

  8. Cialis and Alcohol: Is it Safe?

    www.aol.com/cialis-alcohol-safe-115800912.html

    How Cialis Works. Cialis is a prescription medication designed to treat ED. It’s approved for this use by the U.S. Food and Drug Administration (FDA). Tadalafil is the active ingredient in Cialis.

  9. 4 Common ED Pills: Weighing the Pros & Cons of Each - AOL

    www.aol.com/4-common-ed-pills-weighing-141800609...

    Tadalafil has a half-life of 17.5 hours — it remains active in your body for far longer than other ED medications. A single dose of tadalafil can improve blood flow to your privates and make it ...

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