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Pathogenic bacteria are also the cause of high infant mortality rates in developing countries. [5] A GBD study estimated the global death rates from (33) bacterial pathogens, finding such infections contributed to one in 8 deaths (or ~7.7 million deaths), which could make it the second largest cause of death globally in 2019. [6] [3]
The term "neurovirulent" is used for viruses such as rabies and herpes simplex which can invade the nervous system and cause disease there. [citation needed] Extensively studied model organisms of virulent viruses include virus T4 and other T-even bacteriophages which infect Escherichia coli and a number of related bacteria. [citation needed]
The following outline is provided as an overview of and topical guide to concepts related to infectious diseases in humans.. Infection – transmission, entry/invasion after evading/overcoming defense, establishment, and replication of disease-causing microscopic organisms (pathogens) inside a host organism, and the reaction of host tissues to them and to the toxins they produce.
Human infectious diseases may be characterized by their case fatality rate (CFR), the proportion of people diagnosed with a disease who die from it (cf. mortality rate).It should not be confused with the infection fatality rate (IFR), the estimated proportion of people infected by a disease-causing agent, including asymptomatic and undiagnosed infections, who die from the disease.
The term pathogen came into use in the 1880s. [2] [3] Typically, the term pathogen is used to describe an infectious microorganism or agent, such as a virus, bacterium, protozoan, prion, viroid, or fungus. [4] [5] [6] Small animals, such as helminths and insects, can also cause or transmit disease.
Tuberculosis (TB), also known colloquially as the "white death", or historically as consumption, [7] is a contagious disease usually caused by Mycobacterium tuberculosis (MTB) bacteria. [1] Tuberculosis generally affects the lungs , but it can also affect other parts of the body. [ 1 ]
"Germ" refers not just to bacteria but to any type of microorganism, such as protists or fungi, or other pathogens, including parasites, viruses, prions, or viroids. [1] Diseases caused by pathogens are called infectious diseases. Even when a pathogen is the principal cause of a disease, environmental and hereditary factors often influence the ...
Graphic depicting the human skin microbiota, with relative prevalences of various classes of bacteria. The human microbiome is the aggregate of all microbiota that reside on or within human tissues and biofluids along with the corresponding anatomical sites in which they reside, [1] [2] including the gastrointestinal tract, skin, mammary glands, seminal fluid, uterus, ovarian follicles, lung ...