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database of protein similarities computed using FASTA: Protein model databases Swiss-model: server and repository for protein structure models Protein model databases AAindex: database of amino acid indices, amino acid mutation matrices, and pair-wise contact potentials Protein model databases BioGRID: Samuel Lunenfeld Research Institute
Relational database concepts of computer science and Information retrieval concepts of digital libraries are important for understanding biological databases. Biological database design, development, and long-term management is a core area of the discipline of bioinformatics. [3]
Version 2.0 was released in 2001 and included the capability to link to information available in other databases. [5] Version 3.0 (2002) expanded the database from physical/biochemical interactions to also include genetic interactions. [8] Version 3.5 (2004) included a refined user-interface that aimed to simplify information retrieval. [7]
The NCBI houses a series of databases relevant to biotechnology and biomedicine and is an important resource for bioinformatics tools and services. Major databases include GenBank for DNA sequences and PubMed, a bibliographic database for biomedical literature. Other databases include the NCBI Epigenomics database.
Logo Expasy 2020. Expasy is an online bioinformatics resource operated by the SIB Swiss Institute of Bioinformatics.It is an extensible and integrative portal which provides access to over 160 databases and software tools and supports a range of life science and clinical research areas, from genomics, proteomics and structural biology, to evolution and phylogeny, systems biology and medical ...
[4] [5] [6] These databases coexisted with differing protein sequence coverage and annotation priorities. Swiss-Prot was created in 1986 by Amos Bairoch during his PhD and developed by the Swiss Institute of Bioinformatics and subsequently developed by Rolf Apweiler at the European Bioinformatics Institute .
KEGG (Kyoto Encyclopedia of Genes and Genomes) is a collection of databases dealing with genomes, biological pathways, diseases, drugs, and chemical substances.KEGG is utilized for bioinformatics research and education, including data analysis in genomics, metagenomics, metabolomics and other omics studies, modeling and simulation in systems biology, and translational research in drug development.
The Database of Macromolecular Motions is a bioinformatics database and software-as-a-service tool that attempts to categorize macromolecular motions, sometimes also known as conformational change. [ 4 ] [ 5 ] [ 6 ] It was originally developed by Mark B. Gerstein , Werner Krebs , and Nat Echols in the Molecular Biophysics & Biochemistry ...