Search results
Results from the WOW.Com Content Network
The main side effects of vincristine are chemotherapy-induced peripheral neuropathy, hyponatremia, constipation, and hair loss. Vincristine-induced neuropathy is the main dose-limiting side effect. [9] Chemotherapy-induced peripheral neuropathy can be severe, and may be a reason to reduce or avoid using vincristine.
While metamizole is a relatively safe medication, [24] it is not entirely devoid of adverse effects. [ 24 ] Metamizole has a potential of blood-related toxicity (blood dyscrasias ), but causes less kidney , cardiovascular , and gastrointestinal toxicity than non-steroidal anti-inflammatory drugs (NSAIDs). [ 11 ]
Vinblastine is a vinca alkaloid [10] [3] [11] and a chemical analogue of vincristine. [12] [13] It binds tubulin, thereby inhibiting the assembly of microtubules. [14]Vinblastine treatment causes M phase specific cell cycle arrest by disrupting microtubule assembly and proper formation of the mitotic spindle and the kinetochore, each of which are necessary for the separation of chromosomes ...
GLP-1 drugs used for weight loss involve all kinds of side effects—good and not-so-good—that may or may not strike the average user. (Reminder that there are many of these meds now.
Milk-alkali syndrome is an illness that is characterized by hypercalcaemia, kidney damage, and metabolic alkalosis. [17] This syndrome was discovered in the early 1900s when people began experiencing adverse effects from Bertrand Sippy's gastric ulcer treatment consisting of milk and alkali.
The importance of ecopharmacovigilance is to monitor adverse effects of pharmaceuticals on humans through environmental exposure. [ citation needed ] Due to this relatively new field of science, researchers are continuously developing and understanding the impacts of pharmaceuticals in the environment and its risk on human and animal exposure.
It was found to possess higher anti-gram negative potency than standard quinolones, and showed some anti-gram positive effects. [55] Both its blood serum levels and tissue penetration abilities proved to be poor, and it was overshadowed by the development of ciprofloxacin, a fluoroquinolone with a superior spectrum of activity. [ 47 ]
Cysteamine and methionine have also been used to prevent hepatotoxicity, [69] although studies show that both are associated with more adverse effects than acetylcysteine. [20] Additionally, acetylcysteine has been shown to be a more effective antidote, particularly in patients presenting greater than 8 hours post-ingestion [ 70 ] and for those ...