Search results
Results from the WOW.Com Content Network
Adipocytes, also known as lipocytes and fat cells, are the cells that primarily compose adipose tissue, specialized in storing energy as fat. [1] Adipocytes are derived from mesenchymal stem cells which give rise to adipocytes through adipogenesis. In cell culture, adipocyte progenitors can also form osteoblasts, myocytes and other cell types.
Adipose tissue (also known as body fat or simply fat) is a loose connective tissue composed mostly of adipocytes. [1] [2] It also contains the stromal vascular fraction (SVF) of cells including preadipocytes, fibroblasts, vascular endothelial cells and a variety of immune cells such as adipose tissue macrophages.
These genes include adipocyte protein (aP2), insulin receptor, glycerophosphate dehydrogenase, fatty acid synthase, acetyl CoA carboxylase, glucose transporter type 4 (Glut 4) and so on. [6] Through this process, lipid droplets accumulate in the adipocyte. However, preadipocytes cell lines have difficult to different to differentiate into ...
In biochemistry, lipogenesis is the conversion of fatty acids and glycerol into fats, or a metabolic process through which acetyl-CoA is converted to triglyceride for storage in fat. [1]
Whether they rely entirely on free fatty acids absorbed from the blood, or are able to synthesize their own fatty acids from blood glucose, is not known. The cells of the central nervous system will almost certainly have the capability of manufacturing their own fatty acids, as these molecules cannot reach them through the blood–brain barrier ...
This mutant strain, called "4D," lacks neutral lipids and lipid droplets (LDs), making it ideal for studying Lro1's function. [9] The mutant "4D" yeast cells cannot survive under nutrient-poor conditions because they cannot make triacylglycerol (TG) or lipid droplets (LDs), which are essential for survival during this phase.
In contrast to white adipocytes, which contain a single lipid droplet, brown adipocytes contain numerous smaller droplets and a much higher number of (iron-containing) mitochondria, which gives the tissue its color. [3] Brown fat also contains more capillaries than white fat. These supply the tissue with oxygen and nutrients and distribute the ...
They can be readily distinguished by their expression of TIM4 and MHC class II markers in mice. It was shown that TIM4+ MHCII- macrophages originate in the embryo, even before adipocytes are fully formed, while TIM4- MHCII+ arise in the bone marrow. [6] The formation of ATM identity critically depends on the transcription factor c-Maf. [6]