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Harpagoside is a natural product found in the plant Harpagophytum procumbens, also known as devil's claw. [1] It is the active chemical constituent responsible for the medicinal properties of the plant, which have been used for centuries by the Khoisan people of southern Africa to treat diverse health disorders, including fever, diabetes, hypertension, and various blood related diseases.
Beyond adverse effects from the herb itself, "adulteration, inappropriate formulation, or lack of understanding of plant and drug interactions have led to adverse reactions that are sometimes life threatening or lethal." [3]
Preparations of the plant or its extracts, such as harpagoside, [5] are presumed to have uses in folk medicine and phytotherapy as an anti-inflammatory herbal drug or dietary supplement. [1] Although there is no accepted clinical evidence of its efficacy and bioavailability, limited effects were noted for treating lower back pain and ...
Fish oil supplements containing omega-3 fatty acids can lower risk factors for heart disease, and supplements containing prebiotics and probiotics are looking like they may be future game-changers ...
They may not be upfront about the actual ingredients in those supplements or the possible side effects, which pose unique risks for certain breast and endometrial cancer patients.
A new report by Consumer Reports Magazine says dietary supplements sold in the U.S. are often contaminated and may cause serious health problems. The report says of the more than 54,000 ...
Supplements also aren’t regulated by the U.S. Food and Drug Administration (FDA) for safety and effectiveness. However, there is one supplement Pollan says he takes daily: a multivitamin ...
With few exceptions, like some vitamins from B-complex, hypervitaminosis usually occurs with the fat-soluble vitamins A and D, which are stored, respectively, in the liver and fatty tissues of the body. These vitamins build up and remain for a longer time in the body than water-soluble vitamins. [2] Conditions include: Hypervitaminosis A