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Disulfiram-alcohol reaction (DAR) is the effect of the interaction in the human body of alcohol drunk with disulfiram or some types of mushrooms. [ 1 ] [ 2 ] The DAR is key to disulfiram therapy that is widely used for alcohol-aversive treatment and management of other addictions (e.g. cocaine [ 3 ] [ 4 ] use).
[1] [2] The reaction has been variously termed a disulfiram-like reaction, alcohol intolerance, and acetaldehyde syndrome. [ 3 ] The prototypical drug of this group is disulfiram (brand name Antabuse), which acts as an acetaldehyde dehydrogenase inhibitor , preventing the metabolism of acetaldehyde into acetic acid , and is used in the ...
A 0-0-1-3 program was also implemented by the senior administration of the United States Naval Academy in response to a string of alcohol-related incidents that generated a large amount of negative publicity during the 2005-2006 school year. Its primary aim there is to "promote responsible alcohol use" within the brigade of midshipmen.
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The Severity of Alcohol Dependence Questionnaire (SADQ or SAD-Q) is a 20 item clinical screening tool designed to measure the presence and level of alcohol dependence. [1] It is divided into five sections: Physical withdrawal symptoms; Affective withdrawal symptoms; Craving and relief drinking; Typical daily consumption
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This combination's goal is to prolong the empathogenic effects of MDMA and the psychedelic effects of LSD. The idea is to have be able to experience an enhanced "Candyflipping" with a smoother comedown. The whole experience is long-lasting and can be too intense as all of these molecules synergize and potentiate each other. 2C-B: MDMA: Nexus ...
The Alcohol and Drug Foundation was established in 1959 as the Alcoholism Foundation of Victoria. It was a response to the lack of services for alcohol-dependent people at the time and provided counselling and information. In those days, the Foundation called for a "coordinated attack by the community, involving education, treatment, and ...