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  2. Boceprevir - Wikipedia

    en.wikipedia.org/wiki/Boceprevir

    The RESPOND-2 trial [11] studied patients with chronic hepatitis C genotype 1 who did not have a sustained response to therapy with peginterferon-ribavirin therapy. All patients received a month of peginterferon alfa-2b and ribavirin before being randomized to one of three arms. The first arm received placebo plus peginterferon-ribavirin for 44 ...

  3. Simeprevir - Wikipedia

    en.wikipedia.org/wiki/Simeprevir

    Simeprevir, sold under the brand name Olysio among others, is a medication used in combination with other medications for the treatment of hepatitis C. [2] It is specifically used for hepatitis C genotype 1 and 4. [2] Medications it is used with include sofosbuvir or ribavirin and peginterferon-alfa. [2] Cure rates are in 80s to 90s percent.

  4. Telaprevir - Wikipedia

    en.wikipedia.org/wiki/Telaprevir

    The cost of telaprevir-based triple therapy for hepatitis C is $189,000 per sustained viral response. [11] On August 12, 2014, Vertex Pharmaceuticals announced that it would discontinue production of its brand of telaprevir, Incivek, due to falling demand for the drug caused by competition from newer hepatitis C treatments. [12]

  5. Understanding hepatitis C: A growing public health concern - AOL

    www.aol.com/news/understanding-hepatitis-c...

    Mar. 14—Hepatitis C is a liver infection caused by the hepatitis C virus. It is becoming a big public health concern in many counties, including Lawrence County, encouraging us to review some ...

  6. Sofosbuvir/velpatasvir - Wikipedia

    en.wikipedia.org/wiki/Sofosbuvir/velpatasvir

    Common side effects (in more than 10% of people) are headache, fatigue and nausea. [9] [8] In studies, severe side effects were experienced in 3% of patients, and 0.2% terminated the therapy because of adverse events. These effects occurred with similar frequencies in people treated with placebo. [11]

  7. Elbasvir/grazoprevir - Wikipedia

    en.wikipedia.org/wiki/Elbasvir/grazoprevir

    Elbasvir/grazoprevir, sold under the brand name Zepatier, is a fixed-dose combination for the treatment of hepatitis C, containing elbasvir (an inhibitor of hepatitis C virus's NS5A protein) and grazoprevir (an NS3/4A inhibitor). It is used to treat chronic hepatitis C virus (HCV) genotypes 1 or 4 infection in both treatment-naïve and ...

  8. Sofosbuvir - Wikipedia

    en.wikipedia.org/wiki/Sofosbuvir

    Compared to previous treatments, sofosbuvir-based regimens provide a higher cure rate, fewer side effects, and a two- to four-fold reduction in therapy duration. [ 17 ] [ 18 ] [ 19 ] Sofosbuvir allows most people to be treated successfully without the use of peginterferon, an injectable drug with severe side effects that is a key component of ...

  9. Ledipasvir - Wikipedia

    en.wikipedia.org/wiki/Ledipasvir

    Ledipasvir is a drug for the treatment of hepatitis C that was developed by Gilead Sciences. [1] After completing Phase III clinical trials, on February 10, 2014, Gilead filed for U.S. approval of a ledipasvir/sofosbuvir fixed-dose combination tablet for genotype 1 hepatitis C. [2] [3] The ledipasvir/sofosbuvir combination is a direct-acting antiviral agent that interferes with HCV replication ...

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