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Production problems were most likely due to the attempt to mass-produce phages when they were barely understood. The phages may have been damaged and/or too low in concentration. Another possibility is that incorrect diagnoses led to the use of the irrelevant types of phages that were not adapted to the host bacteria of interest. Many studies ...
George Eliava pioneered the use of phages in treating bacterial infections. Phages were discovered to be antibacterial agents and were used in the former Soviet Republic of Georgia (pioneered there by Giorgi Eliava with help from the co-discoverer of bacteriophages, Félix d'Hérelle) during the 1920s and 1930s for treating bacterial infections.
While knowledge was being accumulated regarding the biology of phages and how to use phage cocktails correctly, early uses of phage therapy were often unreliable. [29] Since the early 20th century, research into the development of viable therapeutic antibiotics had also been underway, and by 1942, the antibiotic penicillin G had been ...
In 1946, Luria made a finding that was destined to open up a new insight on how the stability of DNA is achieved (see Luria, [5] pg. 96). What he discovered was that when, after UV irradiation, two or more "dead" phage entered the same bacterial cell, they often became alive again and produced normal live progeny. [9]
The neutral powers were countries that remained neutral during World War II.Some of these countries had large colonies abroad or had great economic power. Spain had just been through its civil war, which ended on 1 April 1939 (five months prior to the invasion of Poland)—a war that involved several countries that subsequently participated in World War II.
The ensuing Black Death may have killed up to 25 million total, including China and roughly a third of the population of Europe and in the next decades, changing the course of Asian and European history. Biologicals were extensively used in many parts of Africa from the sixteenth century AD, most of the time in the form of poisoned arrows, or ...
About 1.2 million Austrians served in all branches of the German armed forces during World War II. After the defeat of the Axis Powers, the Allies occupied Austria in four occupation zones set up at the end of World War II until 1955, when the country again became a fully independent republic under the condition that it remained neutral.
Biological weapons were used against Chinese soldiers and civilians in several military campaigns. [43] In 1940, the Japanese Army Air Force bombed Ningbo with ceramic bombs full of fleas carrying the bubonic plague. [44] Many of these operations were ineffective due to inefficient delivery systems, [42] although up to 400,000 people may have ...