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Pyridoxine/doxylamine, sold under the brand name Diclectin among others, is a combination of pyridoxine hydrochloride (vitamin B 6) and doxylamine succinate.It is generally used for nausea and vomiting of pregnancy (morning sickness); even though its efficacy has not been proven and subsequent research has led to the removal of recommendations in medical journals.
Doxylamine succinate is the active ingredient in many over-the-counter sleep aids branded under various names. Doxylamine succinate and pyridoxine (Vitamin B6) are the ingredients of Diclegis, approved by the FDA in April 2013 becoming the only drug approved for morning sickness [46] with a class A safety rating for pregnancy (no evidence of risk).
While pyridoxine/doxylamine, a combination of vitamin B 6 and doxylamine, is effective in nausea and vomiting of pregnancy, [48] some have questioned its effectiveness in HG. [49] Ondansetron may be beneficial, however, there are some concerns regarding an association with cleft palate, [50] and there is little high-quality data. [46]
Some of the most common pregnancy-related complications or conditions include gestational diabetes, infections, or severe nausea or vomiting. Another common condition that is frequently monitored ...
The recommended adult dose contains: Acetaminophen (650 mg/30 mL) (pain reliever/fever reducer) Dextromethorphan (30 mg/30 mL) (cough suppressant) Doxylamine succinate (12.5 mg/30 mL) (antihistamine/hypnotic) Alcohol (10% by volume) The LiquiCap capsule version has the following active ingredients per pill, half the recommended adult dose:
Coughing, choking, nausea, vomiting, headache, dizziness, and difficulty breathing Cyanide Gas: colorless Odor: bitter almonds Seconds to minutes Moderate dose: headache, nausea, weakness, or anxiety Large dose: loss of consciousness Perfluoroisobutene Gas: colorless Odor: none 1-4 hours Flu-like, also eye, nose, and throat
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