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Azithromycin in conjunction with of chloroquine or hydroxychloroquine has been associated with deleterious outcomes in COVID-19 patients, including drug-induced QT prolongation. [73] After a large-scale trial showed no benefit of using azithromycin in treating COVID-19, the UK's National Institute for Health and Care Excellence (NICE) updated ...
MPR provides detailed information on a wide range of prescription drugs, including: Indications and usage: Descriptions of the approved uses for each medication. Dosage and Administration: Guidelines on how to properly administer the drug, including dosage amounts and frequency. Contraindications: Situations where the drug should not be used.
The Prescribing Information follows one of two formats: "physician labeling rule" format or "old" (non-PLR) format. For "old" format labeling a "product title" may be listed first and may include the proprietary name (if any), the nonproprietary name, dosage form(s), and other information about the product.
Common uses [4] Possible side effects [4] Mechanism of action Aminoglycosides; Amikacin: Amikin: Infections caused by Gram-negative bacteria, such as Escherichia coli and Klebsiella particularly Pseudomonas aeruginosa. Effective against aerobic bacteria (not obligate/facultative anaerobes) and tularemia. All aminoglycosides are ineffective when ...
PPIs may induce common side effects including headache, diarrhoea, abdominal pain, and nausea. Taking PPI may rarely cause community-acquired pneumonia . Prolonged use of PPI may be associated with intestinal Clostridioides difficile infection , low magnesium level , Vitamin B12 and iron deficiency, osteoporosis , acute kidney inflammation, and ...
By inhibiting CYP3A4, macrolide antibitiotics, such as erythromycin and clarithromycin, but not azithromycin, can significantly increase the AUC of the drugs that depend on it for clearance, which can lead to higher risk of adverse effects or drug-drug interactions. Azithromycin stands apart from other macrolide antibiotics because it is a weak ...
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The first line treatments recommended by the U.S. Centers for Disease Control and Prevention are one of four options: azithromycin one gram orally in a single dose, ceftriaxone 250 mg intramuscularly in a single dose, ciprofloxacin 500 mg orally two times a day for three days, or erythromycin base 500 mg orally three times a day for seven days.