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Other common signs include dark urine (bilirubinuria) and pale fatty stool (steatorrhea). [15] Because bilirubin is a skin irritant, jaundice is commonly associated with severe itchiness. [16] [17] Eye conjunctiva has a particularly high affinity for bilirubin deposition due to high elastin content. Slight increases in serum bilirubin can ...
dark urine. swelling in the ankles or legs. persistent itching. pain in the abdomen and back. ... Pale stools that are visibly fatty and/or unusually foul-smelling could (but does not necessarily ...
Conjugated bilirubin, being water-soluble, is excreted through urine. Hence, dark urine tested bilirubin positive signifies conjugated hyperbilirubinemia. [3] A peripheral blood smear showing signs of haemolysis. Red blood cells are normally in a biconcave shape (round cells in this picture).
Clinically, dark urine from hemoglobinuria may be observed because the hemolysis is intravascular (see Pathophysiology below). [4] Blood smear of a patient with Thrombotic Thrombocytopenic Purpura (TTP). Notice that some red blood cells are nucleated. This is a characteristic finding in such blood smears.
The many colors of urine. Urine varies in color from pale yellow to deep amber, primarily due to urochrome, a byproduct of the normal breakdown of red blood cells. ... Dark brown or tea-colored ...
What the symptoms are: Lethargy, nausea, vomiting, loss of appetite, joint pain and dark-colored urine are all common symptoms. Clay- or gray-colored stool, as well as intense itching and ...
These mechanisms are responsible for the dark urine and pale stools observed in biliary obstruction. Low urine urobilinogen may result from complete obstructive jaundice or treatment with broad-spectrum antibiotics , which destroy the intestinal bacterial flora (obstruction of bilirubin passage into the gut or failure of urobilinogen production ...
She adds, “Pale stools, which could suggest a blockage in the bile ducts themselves (especially when coupled with jaundice), should also prompt an expedited evaluation to rule out bile duct ...