Search results
Results from the WOW.Com Content Network
Polygenic. Genetic cause and mechanism of type 2 diabetes is largely unknown. However, single nucleotide polymorphism (SNP) is one of many mechanisms that leads to increased risk for type 2 diabetes. To locate genes and loci that are responsible for the risk of type 2 diabetes, genome wide association studies (GWAS) was utilized to compare the ...
392 million (2015) [11] Type 2 diabetes ( T2D ), formerly known as adult-onset diabetes, is a form of diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin. [6] Common symptoms include increased thirst, frequent urination, fatigue and unexplained weight loss. [3]
Diabetes mellitus cases due to a known defect are classified separately. Type 2 diabetes is the most common type of diabetes mellitus accounting for 95% of diabetes. Many people with type 2 diabetes have evidence of prediabetes (impaired fasting glucose and/or impaired glucose tolerance) before meeting the criteria for type 2 diabetes.
Epidemiology of diabetes. Prevalence (per 1,000 inhabitants) of diabetes worldwide in 2000 - world average was 2.8%. Globally, an estimated 537 million adults are living with diabetes, according to 2019 data from the International Diabetes Federation. [1] Diabetes was the 9th-leading cause of mortality globally in 2020, attributing to over 2 ...
Polyol pathway. The polyol pathway is a two-step process that converts glucose to fructose. [1] In this pathway glucose is reduced to sorbitol, which is subsequently oxidized to fructose. It is also called the sorbitol-aldose reductase pathway . The pathway is implicated in diabetic complications, especially in microvascular damage to the ...
Endocrinology. Complications of diabetes are secondary diseases that are a result of elevated blood glucose levels that occur in diabetic patients. These complications can be divided into two types: acute and chronic. Acute complications are complications that develop rapidly and can be exemplified as diabetic ketoacidosis (DKA), hyperglycemic ...
Diabetic neuropathy is various types of nerve damage associated with diabetes mellitus. The most common form, diabetic peripheral neuropathy, affects 30% all diabetic patients. [1] [2] Symptoms depend on the site of nerve damage and can include motor changes such as weakness; sensory symptoms such as numbness, tingling, or pain; or autonomic ...
History of diabetes. Appearance. Frederick Banting (right) joined by Charles Best in office, 1924. The condition known today as diabetes (usually referring to diabetes mellitus) is thought to have been described in the Ebers Papyrus ( c.1550BC ). Ayurvedic physicians (5th/6th century BC) first noted the sweet taste of diabetic urine, and called ...