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Bromocriptine, originally marketed as Parlodel and subsequently under many brand names, [1] is an ergoline derivative and dopamine agonist that is used in the treatment of pituitary tumors, Parkinson's disease, hyperprolactinaemia, neuroleptic malignant syndrome, and, as an adjunct, type 2 diabetes.
Bromocriptine is a D 2 receptor agonist and D 1 receptor antagonist with a binding affinity to D 2 receptors of anterior pituitary cells, exclusively on lactotrophs. Bromocriptine stimulates Na +, K +-ATPase activity and/or cytosolic Ca 2+ elevation and therefore reduction of prolactin which leads to no production of cAMP.
Prolactin inhibitors are mainly used to treat hyperprolactinemia (high prolactin levels). [1] Agonists of the dopamine D 2 receptor such as bromocriptine and cabergoline are able to strongly suppress pituitary prolactin secretion and thereby decrease circulating prolactin levels, and so are most commonly used as prolactin inhibitors. [1]
Cats aren't just cute and cuddly. There are actually many health benefits of being a cat lover - from lowering blood pressure to reducing stress and anxiety,
Cabergoline is frequently used as a first-line agent in the management of prolactinomas due to its higher affinity for D 2 receptor sites, less severe side effects, and more convenient dosing schedule than the older bromocriptine, though in pregnancy bromocriptine is often still chosen since there is less data on safety in pregnancy for ...
Mayumi Kitakata frets about the health and wellbeing of Chi, her stoic housemate who enjoys treats, indulges a bit too much in the catnip, and about 14 is getting on in years for a feline.
Skin disorders are among the most common health problems in cats and have many causes. The condition of a cat's skin and coat can be an important indicator of its general health. Cheyletiellosis is a mild dermatitis caused by mites of the genus Cheyletiella. It is also known as walking dandruff due to skin scales being carried by the mites ...
This is a collection of articles about the health and care of cats, primarily domestic cats. This includes medical conditions, health issues, parasites, surgical procedures, and similar topics. This includes medical conditions, health issues, parasites, surgical procedures, and similar topics.