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A 2010 (updated in 2023) meta-analysis of 14 randomized controlled trials showed that oral steroids and potent topical steroids are effective treatments, although their use may be limited by side-effects, while lower doses of topical steroids are safe and effective for treatment of moderate bullous pemphigoid. [10]
Mucous membrane pemphigoid is a rare chronic autoimmune subepithelial blistering disease characterized by erosive lesions of the mucous membranes and skin. [3] It is one of the pemphigoid diseases that can result in scarring.
Some women with autoimmune diseases may have problems getting pregnant. This can happen for many reasons such as medication types or even disease types. [59] Tests can tell if fertility problems are caused by an autoimmune disease or an unrelated reason. Fertility treatments are able to help some women with autoimmune disease become pregnant. [2]
Linear IgA bullous dermatosis is a rare immune-mediated blistering skin disease frequently associated with medication exposure, especially vancomycin, with men and women being equally affected. [ 2 ] : 135 It was first described by Tadeusz Chorzelski in 1979 and may be divided into two types: [ 3 ] : 587
Bullous pemphigoid is primarily a disease of older adults and it rarely occurs in children. The vast majority of cases involved individuals between the ages of 60 and 80 years. Two European studies have also suggested the increased risk of bullous pemphigoid with advancing age. [28] [29]
Gestational pemphigoid: IgG1: NC16A terminal of BPAG2 BPAG1: 180 230 Cicatricial pemphigoid: C-terminal of BPAG2: 180 Ocular cicatricial pemphigoid: Integrin beta-4 subunit: 200 Antiepiligrin cicatricial pemphigoid [nb 1] Laminin 5 (Epiligrin, Laminin 332) Linear IgA bullous dermatosis: LAD1 portion of BPAG2 Collagen type VII: 97 290/145 ...
Tetracycline antibiotics have a mildly beneficial effect on the disease and are sometimes enough for pemphigus foliaceus. In addition, talcum powder is helpful to prevent oozing sores from adhering to bedsheets and clothes. Wound care and treatments are often akin to those used in burn units, including careful use of dressings that don't stick ...
Paraneoplastic pemphigus (PNP) is an autoimmune disorder stemming from an underlying tumor.It is hypothesized that antigens associated with the tumor trigger an immune response resulting in blistering of the skin and mucous membranes.
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