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In the large intestines, villi are absent and a flat surface with thousands of glands is observed. Underlying the epithelium is the lamina propria, which contains myofibroblasts, blood vessels, nerves, and several different immune cells, and the muscularis mucosa which is a layer of smooth muscle that aids in the action of continued peristalsis ...
The cecum – the first part of the large intestine Taeniae coli – three bands of smooth muscle; Haustra – bulges caused by contraction of taeniae coli; Epiploic appendages – small fat accumulations on the viscera; The taenia coli run the length of the large intestine.
Smooth muscle is grouped into two types: single-unit smooth muscle, also known as visceral smooth muscle, and multiunit smooth muscle. Most smooth muscle is of the single-unit type, and is found in the walls of most internal organs (viscera); and lines blood vessels (except large elastic arteries), the urinary tract , and the digestive tract .
The muscularis mucosae (or lamina muscularis mucosae) is a thin layer of muscle of the gastrointestinal tract, located outside the lamina propria, and separating it from the submucosa. It is present in a continuous fashion from the esophagus to the upper rectum (the exact nomenclature of the rectum's muscle layers is still being debated).
The interstitial cells of Cajal are specialized pacemaker cells [3] located in the wall of the stomach, small intestine, and large intestine. [1] These cells are connected to the smooth muscle via gap junctions and the myenteric plexus. The cell membranes of the pacemaker cells undergo a rhythmic depolarization and repolarization from -65mV to ...
The internal anal sphincter is the specialised thickened terminal portion of the inner circular layer of smooth muscle of the large intestine. It extends from the pectinate line (anorectal junction) proximally to just proximal to the anal orifice distally (the distal termination is palpable). Its muscle fibres are arranged in a spiral (rather ...
The lower gastrointestinal tract includes most of the small intestine and all of the large intestine. [15] In human anatomy , the intestine ( bowel or gut ; Greek: éntera ) is the segment of the gastrointestinal tract extending from the pyloric sphincter of the stomach to the anus and as in other mammals, consists of two segments: the small ...
The stimulation for these contractions likely originates in modified smooth muscle cells called interstitial cells of Cajal. These cells cause spontaneous cycles of slow wave potentials that can cause action potentials in smooth muscle cells. They are associated with the contractile smooth muscle via gap junctions.