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Sweet syndrome (SS), or acute febrile neutrophilic dermatosis, [1] [2] is a skin disease characterized by the sudden onset of fever, an elevated white blood cell count, and tender, red, well-demarcated papules and plaques that show dense infiltrates by neutrophil granulocytes on histologic examination.
Reactive neutrophilic dermatoses are a spectrum of conditions mediated by neutrophils, and typically associated with underlying diseases, such as inflammatory bowel disease and hematologic malignancy.
Sweet's syndrome-like dermatosis is a cutaneous condition associated with bowel disorders. [1] See also. Sweet's syndrome; List of cutaneous conditions; References
Pyogenic arthritis–pyoderma gangrenosum–acne syndrome (PAPA syndrome) Rheumatoid neutrophilic dermatitis (rheumatoid neutrophilic dermatosis) Superficial granulomatous pyoderma; Sweet's syndrome (acute febrile neutrophilic dermatosis) Sweet's syndrome-like dermatosis; Vesicopustular dermatosis
Early linear IgA bullous dermatosis Subepidermal blister formation. [26] Early febrile neutrophilic dermatosis (Sweet's syndrome) Neutrophilic and lymphohistiocytic infiltrate and edema. [27] Connective tissue disorders Usually associated with epidermal changes. [2] (Systemic lupus erythematosis pictured) Cutaneous small-vessel vasculitis
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A hereditary disorder driven by pyrin mutation, called PAAND (Pyrin-associated autoinflammation with neutrophilic dermatosis), [7] is characterized by neutrophilic dermatosis, recurrent fever, increased acute-phase reactants, arthralgia, or myalgia.
LPIN2, D18S60. Synonyms: Majeed syndrome. Complement component 2 deficiency: Possibly symptomatic of autoimmune diseases, but not a disease. Congenital heart block: May be related to autoimmune activity in the mother. Contact dermatitis: A hypersensitivity. Cushing's syndrome: No consistent evidence of association with autoimmunity.