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  2. Disease-modifying osteoarthritis drug - Wikipedia

    en.wikipedia.org/wiki/Disease-modifying...

    Paradigm's IND application to commence its phase 3 pivotal clinical trial investigating Pentosan Polysulphate Sodium (PPS) for the treatment of pain associated with knee osteoarthritis has been cleared by the US FDA. Approximately 65 sites have been identified throughout the US and Australia. Contracting with many of those sites has been completed.

  3. Injectable filler - Wikipedia

    en.wikipedia.org/wiki/Injectable_filler

    Injectable filler is a special type of substance made for injections into connective tissues, such as skin, cartilage or even bone, for cosmetic or medical purposes.The most common application of injectable fillers is to change one's facial appearance, but they also are used to reduce symptoms of osteoarthritis, treat tendon or ligament injuries, support bone and gum regeneration, and for ...

  4. Arthroplasty - Wikipedia

    en.wikipedia.org/wiki/Arthroplasty

    [medical citation needed] For example, a hip joint that is affected by osteoarthritis may be replaced entirely (total hip arthroplasty) with a prosthetic hip. This would involve replacing both the acetabulum (hip socket) and the head and neck of the femur. The purpose of this procedure is to relieve pain, to restore range of motion and to ...

  5. Knee cartilage replacement therapy - Wikipedia

    en.wikipedia.org/wiki/Knee_cartilage_replacement...

    Osteoarthritis is a common condition of cartilage failure that can lead to limited range of motion, bone damage and invariably, pain. Due to a combination of acute stress and chronic fatigue, osteoarthritis directly manifests itself in a wearing away of the articular surface and, in extreme cases, bone can be exposed in the joint.

  6. US FDA warns of harmful reactions to fake Botox injections - AOL

    www.aol.com/news/us-fda-warns-harmful-reactions...

    The U.S. Centers for Disease Control and Prevention (CDC) and the FDA are investigating reports of harmful reactions among people who received injections of counterfeit Botox. As of April 12, a ...

  7. Botulinum toxin - Wikipedia

    en.wikipedia.org/wiki/Botulinum_toxin

    Botulinum toxin, or botulinum neurotoxin (commonly called botox), is a neurotoxic protein produced by the bacterium Clostridium botulinum and related species. [24] It prevents the release of the neurotransmitter acetylcholine from axon endings at the neuromuscular junction, thus causing flaccid paralysis. [25]

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