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Cerebrotendinous xanthomatosis (CTX), also called cerebral cholesterosis, [1] is a rare inborn bile acid metabolism disorder caused by autosomal-recessive mutations in the CYP27A1 gene. [2] CTX is characterized by a wide range of symptoms, including neurological and non-neurological issues.
A cataract is a cloudy area in the lens of the eye that leads to a decrease in vision of the eye. [1] [7] Cataracts often develop slowly and can affect one or both eyes. [1] Symptoms may include faded colours, blurry or double vision, halos around light, trouble with bright lights, and difficulty seeing at night. [1]
Charles David Kelman (May 23, 1930 – June 1, 2004) was an American ophthalmologist, surgeon, inventor, jazz musician, entertainer, and Broadway producer. Known as the father of phacoemulsification, [1] [2] he developed many of the medical devices, instruments, implant lenses and techniques used in cataract surgery.
CTX is a three-letter abbreviation with multiple meanings: Medical. C-terminal telopeptide, a blood serum biomarker that can be measured to assess bone turnover;
Visual or vision impairment (VI or VIP) is the partial or total inability of visual perception.In the absence of treatment such as corrective eyewear, assistive devices, and medical treatment, visual impairment may cause the individual difficulties with normal daily tasks, including reading and walking. [6]
Childhood cataracts are the primary cause of childhood blindness. [4] Childhood cataracts make up 7.4% to 15.3% of blindness in kids. [4] The prevalence of childhood cataracts ranges from 0.63/10,000 to 9.74/10,000 children, with a median of 1.71. [6] This is dependent on factors like economic status but not gender or laterality. [6]
Taylor was born in Norwich, possibly in 1703. [2] He was the son of a surgeon named John Taylor, who died in 1709. [2] He studied in London under the pioneering British surgeon William Cheselden at St Thomas' Hospital, [2] and by 1727 had produced a book, An Account of the Mechanism of the Eye, dedicated to Cheselden.
Congenital cataracts are a lens opacity that is present at birth. Congenital cataracts occur in a broad range of severity. Some lens opacities do not progress and are visually insignificant, others can produce profound visual impairment. Congenital cataracts may be unilateral or bilateral. They can be classified by morphology, presumed or ...