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  2. Switching Antidepressants: Safety, Side Effects & Other ... - AOL

    www.aol.com/switching-antidepressants-safety...

    Since some tricyclic antidepressants (TCAs) and monoamine oxidase inhibitors (MAOIs) can cause harmful interactions if used within 14 days of starting treatment with other antidepressants, you may ...

  3. Orthostatic hypotension - Wikipedia

    en.wikipedia.org/wiki/Orthostatic_hypotension

    Orthostatic hypotension may cause accidental falls. [11] It is also linked to an increased risk of cardiovascular disease, heart failure, and stroke. [42] [27] Also, observational data suggest that orthostatic hypotension in middle age increases the risk of eventual dementia and reduced cognitive function. [43]

  4. Sertraline - Wikipedia

    en.wikipedia.org/wiki/Sertraline

    Sertraline, sold under the brand name Zoloft among others, is an antidepressant medication of the selective serotonin reuptake inhibitor (SSRI) class [10] used to treat major depressive disorder, generalized anxiety disorder, social anxiety disorder, obsessive–compulsive disorder (OCD), panic disorder, and premenstrual dysphoric disorder. [11]

  5. Sertraline for Depression & Anxiety: What Are the Possible ...

    www.aol.com/sertraline-depression-anxiety...

    Sertraline is approved to treat a variety of conditions, including depression and anxiety, and, although no antidepressant works for everybody, experts generally agree that it’s one of the most ...

  6. Selective serotonin reuptake inhibitor - Wikipedia

    en.wikipedia.org/wiki/Selective_serotonin...

    Selective serotonin reuptake inhibitors (SSRIs) are a class of drugs that are typically used as antidepressants in the treatment of major depressive disorder, anxiety disorders, and other psychological conditions. SSRIs increase the extracellular level of the neurotransmitter serotonin by limiting its reabsorption (reuptake) into the ...

  7. Alpha-1 blocker - Wikipedia

    en.wikipedia.org/wiki/Alpha-1_blocker

    By reducing alpha-1-adrenergic activity of the blood vessels, these drugs may cause hypotension (low blood pressure) and interrupt the baroreflex response. In doing so, they may cause dizziness, lightheadedness, or fainting when rising from a lying or sitting posture (known as orthostatic hypotension or postural hypotension). For this reason ...

  8. Pure autonomic failure - Wikipedia

    en.wikipedia.org/wiki/Pure_autonomic_failure

    Within three minutes of standing up straight, orthostatic hypotension is defined as a drop in systolic blood pressure of at least 20 mm Hg or a drop in diastolic blood pressure of 10 mm Hg. [7] About half of PAF patients also have concurrent supine hypertension, even though all PAF patients by definition have orthostatic hypotension. [8]

  9. Development and discovery of SSRI drugs - Wikipedia

    en.wikipedia.org/wiki/Development_and_discovery...

    [5] [6] Because of this, researchers looked for other alternatives with similar effectiveness but fewer adverse effects e.g. drugs that did not cause cardiac conduction abnormalities in overdoses or have the tendency to cause seizures, [7] which led to the discovery of the SSRI drugs. The SSRIs are the most significant class of antidepressants ...