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Carbonic acid is a chemical compound with the chemical formula H 2 C O 3. The molecule rapidly converts to water and carbon dioxide in the presence of water. However, in the absence of water, it is quite stable at room temperature .
As calculated by the Henderson–Hasselbalch equation, in order to maintain a normal pH of 7.4 in the blood (whereby the pK a of carbonic acid is 6.1 at physiological temperature), a 20:1 ratio of bicarbonate to carbonic acid must constantly be maintained; this homeostasis is mainly mediated by pH sensors in the medulla oblongata of the brain ...
3 (i.e. the first acid dissociation constant for carbonic acid), K 2 is the equilibrium constant for the reaction HCO − 3 ⇌ H + + CO 2− 3 (i.e. the second acid dissociation constant for carbonic acid), and DIC is the (unchanging) total concentration of dissolved inorganic carbon in the system, i.e. [CO 2] + [HCO − 3] + [CO 2− 3].
Most carbonic acid then dissociates to bicarbonate and hydrogen ions. One of the buffer systems present in the body is the blood plasma buffering system. This is formed from , carbonic acid, working in conjunction with [HCO − 3], bicarbonate, to form the bicarbonate system. [10]
In inorganic chemistry, bicarbonate (IUPAC-recommended nomenclature: hydrogencarbonate [2]) is an intermediate form in the deprotonation of carbonic acid. It is a polyatomic anion with the chemical formula H C O − 3. Bicarbonate serves a crucial biochemical role in the physiological pH buffering system. [3]
The inorganic cycle begins with the production of carbonic acid (H 2 CO 3) from rainwater and gaseous carbon dioxide. [6] Due to this process, normal rain has a pH of around 5.6. [ 7 ] Carbonic acid is a weak acid , but over long timescales, it can dissolve silicate rocks (as well as carbonate rocks).
Carbonation is the chemical reaction of carbon dioxide to give carbonates, bicarbonates, and carbonic acid. [1] In chemistry, the term is sometimes used in place of carboxylation, which refers to the formation of carboxylic acids. In inorganic chemistry and geology, carbonation is common.
The most abundant buffer in the ECF consists of a solution of carbonic acid (H 2 CO 3), and the bicarbonate (HCO − 3) salt of, usually, sodium (Na +). [5] Thus, when there is an excess of OH − ions in the solution carbonic acid partially neutralizes them by forming H 2 O and bicarbonate (HCO − 3) ions.