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The major tissues affected are nerves and muscles, where irreversible damage starts to occur after 4–6 hours of cessation of blood supply. [4] Skeletal muscle, the major tissue affected, is still relatively resistant to infarction compared to the heart and brain because its ability to rely on anaerobic metabolism by glycogen stored in the cells may supply the muscle tissue long enough for ...
Plaque can limit the supply of blood and oxygen to your heart tissue. Many people with early coronary artery disease don’t have any symptoms. If your heart doesn’t get enough oxygen, you might ...
A condition called peripheral artery disease (PAD), for example, occurs when the arteries that carry blood from the heart to the legs get clogged; it’s associated with an increased risk of heart ...
If blood flow through the coronary arteries is stopped completely, cardiac muscle cells may die, known as a myocardial infarction, or heart attack. [9] Coronary artery disease (CAD) is the most common cause of coronary ischemia. [7] Coronary ischemia and coronary artery disease are contributors to the development of heart failure over time. [10]
On the other hand, when the symptoms exceed 14 days, [3] it is called critical limb ischemia (CLI). CLI is the end stage of peripheral vascular disease where there is still some collateral circulation (alternate circulation pathways) that bring some blood flow (although inadequate) to the distal parts of the limbs. [ 2 ]
People who have HCM may have a range of symptoms. People may be asymptomatic, or may have fatigue, leg swelling, and shortness of breath. [2] It may also result in chest pain or fainting. [2] Symptoms may be worse when the person is dehydrated. [10] Complications may include heart failure, an irregular heartbeat, and sudden cardiac death. [3] [4]
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